Search Results for: Genetics

Weekly reads: our new brain tumor paper, levitation, dear doctor, Japan, more

brain tumor, H3.3 K27M, ASCL1

There’s nothing quite like getting a new paper out as a scientist running a research lab so this week we can celebrate our new pediatric brain tumor study. I’ll start the weekly reads with that paper. Of course, getting new grants is amazing too but there’s more of a feel of completion after a paper […]

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Weekly reads: neural stem cells, CRISPR brain, Vertex, cytoplasm surprise

neural stem cells

Some people consider the brain to be equivalent to a living computer and in that sense it’s too bad that computers don’t have the equal of neural stem cells to help them fix themselves. Is the internet one big neural network-like web? There was a quake in the stem cell internet as CIRM’s main website

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Recommend reads: CRISPR baby guy free, DNMT3, sperm, Editas, hearing loss, reprogramming

Dura et al sperm development

We often don’t think of them that way but reproductive cells like sperm and egg are also relatives of stem cells, and it turns out that there are stem cells that make the reproductive cells too like sperm stem cells. Sperm and germ cell stem cells DNMT3A-dependent DNA methylation is required for spermatogonial stem cells

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All about Altos Labs & its $3B cellular rejuvenation push

Altos Labs PIs

I wrote briefly a few months ago about Altos Labs. It’s a new kind of biotech institute that is focused on cellular reprogramming. Now we know much more and it’s clear this is a huge deal. What’s in this article What is Altos Labs? | Cellular rejuvenation | Reprogramming oldness | Challenges | Altos Strategies | Analysis of

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If you lost a loved one, could you turn to human cloning?

Human-cloning

One of the most interesting parts of running a website like The Niche is that reader’s questions can sometimes be so striking including recent ones on human cloning. They got me thinking about cloning again. Human cloning & loss of a loved one: things to consider Several readers have recently asked about whether human cloning

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Grading my 21 stem cell & regenerative medicine predictions for 2021

stem-cell-crystal-ball-300x3001

The world of stem cell research and regenerative medicine is unpredictable but it’s fun to be a part of it and try to do predictions. Each year in late December or early January I make prognostications for the coming year for stem cell research and regenerative medicine. I made 21 such predictions for the current

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Explainer on 293 or HEK cells and their use in COVID vaccine research

HEK 293 cells Knoepfler Lab

A type of human cells used in research called HEK cells or 293s has been much in the news lately. This is mainly related to COVID-19 vaccine research. There seem to be many misunderstandings about 293 cells. For that reason, I thought I’d do this post to clear things up. I’ve been working with these

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The Niche weekend reads: Editas mess, The Niche updates, papers

The news of the week relates to an interim clinical trial report from gene-editing firm Editas on its CRISPR trial for a form of vision loss. On to that in a minute. What have you been reading the past week? Below, I include our weekly list of recommended reads. However, first I wanted to give

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