The paper that came out Wednesday from a research group in China reporting the first genetic modification of human embryos has sparked a lot of discussion. Some concerns about this paper have surfaced. 2-day review? The paper (HT to John Borghi) was in review only from March 30-April 1 — so at most 48 hours. Really? That certainly …
Concerns surface on Chinese paper on genetic modification of human embryos Read More »
There is a big old blind spot in the discussion over germline gene editing in humans: preimplantation genetic diagnosis (PGD). There’s been a lot of talk in 2015 about worries over how gene editing technology such as CRISPR might be used prematurely in the clinic in an unsafe or unethical manner in humans in the …
The big blind spot on CRISPR for human embryo editing: PGD Read More »
Rumors have been flying for months that researchers in China and possibly elsewhere were shopping papers around at high-profile journals that reported gene editing and genetic modification of human embryos. Update: apparently this paper (HT to @JohnBorghi) was only reviewed for 2 days (see image at bottom of post), raising major concerns about the depth of …
Researchers in China make genetically modified human embryos Read More »
We’ve all heard the human embryo editing rumors. There is a sense that human embryos have already been CRISPR’d. Rumors are rumors and they may mean not a whole lot, but there definitely is a huge buzz on this right now both in a positive sense and with concern. The excitement is over the power of …
It was intriguing last week to read about another advance in somatic cell nuclear transfer (SCNT)-based therapeutic cloning of human embryonic stem cells (hESC). The first such work was published last year by Mitalipov’s group from OHSU. This second paper to produce so-called nuclear transfer hESC (NT-hESC) made the important advance to show that it could …
The main challenges for SCNT cloning of human embryonic stem cells Read More »
Please note that this is one of the only instances in the history of this blog that I have retroactively edited a post for what I believe was an error on my part related to what I feel was overly extreme verbiage. I have also subsequently been informed confidentially of more of the facts of …
Texas Guv Perry visits human embryonic stem cell lab at Scripps Institute Read More »
Interestingly, the Komen Foundation appears open to funding human embryonic stem cell (hESC) research. The latest report from Science includes a quote from Komen that denies any changes in funding policy for research and suggests they have not ruled out funding such research: Contrary to circulating online reports, Komen has not “de-funded” any grantee based on human embryonic stem …
Komen Foundation open to funding human embryonic stem cell research Read More »
With the approval today of the use of CRISPR in human embryos, the UK continues its recent trend toward a more permissive regulatory policy on human genetic modification. There are both risks and scientific benefits that come along with this trend. Last year the UK approved an experimental technology with the goal of preventing the …
CRISPR embryo OK signals ongoing liberal UK trend on human modification Read More »
An international team of stem cell scientists has replicated human therapeutic cloning to make embryonic stem cells via somatic cell nuclear transfer (SCNT). The team was led by Drs. Dong Ryul Lee of CHA Stem Cell Institute in Korea and Robert Lanza of Advanced Cell Technology (ACT) and reported the advance in the Chung, et …
Adult human therapeutic cloning of embryonic stem cells by SCNT Read More »
For the first time ever, scientists have successfully used somatic cell nuclear transfer (SCNT) via the process of therapeutic human cloning to generate normal human embryonic stem cells (hESC). Recall that there are two kinds of human cloning: therapeutic (which is reported in the new paper discussed in this post) and reproductive, which is making …
Human cloning successfully makes embryonic stem cells Read More »