Sometimes you think you know a person and they suddenly surprise you by doing something so new that it is shocking or by taking on a new personality. Cells can be that way too. In my book on stem cells, Stem Cells: An Insider’s Guide (you can buy it here on Amazon–it’s very affordable–or also here at […]
New Ways of Thinking About Stem Cells: Book Excerpt Read More »
What does the future hold for CIRM? I asked former CIRM Board Chair and Prop 71 leader, Robert Klein, about that and more in the interview below. He also says some particularly exciting clinical trial and other developments in the stem cell field are coming soon. What got you excited for the very first time
Interview with Robert Klein on CIRM’s Future Read More »
The recent publication of two Nature papers by a team in part led by Dr. Charles Vacanti on acid treatment produced stem cells (so-called STAP stem cells) has been a blockbuster story in the stem cell field and has grabbed major global media attention as well. For background my review of the paper here and more thoughts here. Many
Interview with Charles Vacanti on STAP Cells: Link to Spore Stem Cells & More Read More »
The STAP papers on making iPS like cells using acid treatment of differentiated cells really has people talking. See embryo at right made from GFP reporter STAP cells that glow green. As I said in my review of the papers yesterday, there are still some critical things we do not know about STAP cells and I
More thoughts from STAP acid reprogramming stem cell paper Read More »
In the summer of 2013, the producer and crew of the Discovery Channel’s Through the Wormhole filmed two times at my house for a special episode on stem cells. I think it’s going to be a great show. The stem cell episode will first air on the Science/Discovery Channel on Feb. 3 (check your local listings
Exciting Being on Upcoming ‘Through the Wormhole’ Stem Cells Episode Read More »
The below is an excerpt from my book, Stem Cells: An Insider’s Guide. I hope you enjoy this excerpt and the book, which I think is a really good deal at under $27 paperback or under $17 for E-book version. Having our innovation and ethics too In the stem cell field you can have it
Book Excerpt: Stem Cell For-Profit Good Citizen Biotechs Read More »
2014 Epigenetic mechanisms of tumorigenicity manifesting in stem cells. Tung PY, Knoepfler PS. Oncogene. Jun 16;0. doi: 10.1038/onc.2014.172. [Epub ahead of print] Histone H3.3 regulates dynamic chromatin states during spermatogenesis. Yuen BT, Bush KM, Barrilleaux BL, Cotterman R, Knoepfler PS. Development. 2014 Aug 19. pii: dev.106450. [Epub ahead of print] Miz-1 Activates Gene Expression via a Novel Consensus DNA Binding Motif..
Knoepfler Lab Publications Read More »
Each year I make predictions for the stem cell field for the coming year. In today’s post I write about my top 10 stem cell predictions for 2014. You can see my predictions for 2013 here (see predictions for 2011 and 2012 predictions, which are kind of fun to read to see what was on the “mind” of the field
Stem Cell Predictions for 2014 Read More »
Stem Cells for Alzheimer’s Disease? Below is an excerpt focused on Alzheimer’s Disease from my new book on stem cells. Stem Cells: An Insider’s Guide, which is targeted to a broad audience of people interested in stem cells. Alzheimer’s Disease (AD) is one of the most devastating illnesses. It destroys the brain, which shrinks over
Book Excerpt: Stem Cells for Alzheimer’s Disease–Are We There yet? Read More »
The Knoepfler Lab conducts stem and cancer cell as well as chromatin/epigenetics research at the UC Davis School of Medicine. Our team has two big picture goals: (1) catalyzing the development of more effective treatments for cancers based on targeting stem cell-related machinery in tumorigenesis and (2) producing safer stem cell-based regenerative medicine therapies. We are particularly