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5 new cool stem cell papers worth a look for weekend reading

September 6, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 2 Comments

Some diverse new stem cell papers worth a peek this weekend? Direct reprogramming hits crest: Generation of Multipotent Induced Neural Crest by Direct Reprogramming of Human Postnatal Fibroblasts with a Single Transcription Factor, Cell Stem Cell Hormone receptors in prostate cancer cells versus stem cells: Concise Review: Androgen Receptor Differential Roles in Stem/Progenitor Cells Including Prostate, Embryonic, Stromal, …

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Neuralstem flirting with noncompliance via Right To Try Law?

June 11, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 8 Comments

Is Neuralstem flirting with noncompliance via a Right To Try Law in Colorado? Colorado is an independent-minded state. For example, it is one of only a few states including Washington State with legalized marijuana use. More recently, Colorado passed a new law supported by the ultra-conservative Goldwater Institute, the so-called Right To Try Law. This law …

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What is the FDA’s appropriate role in regulating medical innovations such as stem cells?

February 24, 2014 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 4 Comments

We need medical innovations, but what is the appropriate way for agencies like the FDA to regulate the process and fight bogus interventions based solely on hype? Without innovation, medicine becomes stagnant and hope fades for patients who have any one of numerous conditions that are currently inadequately addressed by medicine. I can relate on …

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23andMe and the FDA: Perspectives on Warning Letter

November 27, 2013 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

What’s the deal with this week’s FDA Warning Letter to 23andMe? First some background. I’m a researcher who studies stem and cancer cell genomics and epigenomics. I’m also a human being who has battled prostate cancer and is curious about my genome. With this background, I decided some time ago to take the plunge and experience what …

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Intuitive Surgical (ISRG) Gets Problematic FDA Inspection Report

July 8, 2013 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 2 Comments

I have some interest in robotic surgery. About three and a half years ago I had surgery for prostate cancer and my surgeon used the da Vinci robotic surgery device made by Intuitive Surgical Inc (ISRG). At the time, da Vinci seemed new and exciting, but the device and the company have become more well-known …

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Cow stem cell fraudsters sent to jail for almost killing human patients: some patients still support them

February 26, 2013 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

Two women in San Diego County are heading to jail after being convicted and sentenced for fraud related to stem cell treatments.The women injected concoctions of bovine stem cells from Germany and DMSO into patients. You can read the details of the original arrest here on the FBI website. According to a Modesto Bee article, Kathleen …

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Some thoughts on life, death, and stem cells

August 26, 2012 February 1, 2021 / By Professor Paul Knoepfler, Ph.D.

I know. I know. Scientists are not supposed to publicly talk about the question of when life begins and about death, but these are kind of important things to talk about and think about, don’t you think? I do. So here goes…. It’s been a very intense, crazy few weeks for me and for many …

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TGIF: stem cell headline weekly review for May 4

May 4, 2012 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 5 Comments

I’m going to try to do a new feature on Fridays, a TGIF review of the week in stem cell headlines in the news. What’s the good, the bad, and the ugly? What’s been hyped? It was a busy week in stem cells. The good Prostate Cancer Stem Cells. I’d give the recent wonderful Cell …

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Vitamin D: is this supplement helpful or hype-ful?

April 18, 2012 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 6 Comments

Is Vitamin D a miracle drug or a disappointment like almost all other vitamins? Just recently there was a piece saying that Vitamin D may reduce pain. Today there was another news article saying Vitamin D may protect men against more aggressive prostate cancer. You name the condition and Vitamin D is claimed to help with …

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Is it fair to tell a patient to be patient?

October 20, 2011 February 1, 2021 / By Professor Paul Knoepfler, Ph.D. / 3 Comments

When I talk to people about stem cell science and the timeline for turning data into treatments and cures, their reactions completely depend on whom they are. Scientists are patient, perhaps too patient….perhaps too understanding of the many years that we are told that science takes to get something to the clinic. Patients and patient …

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