Humans have big brains, right? In fact, they are downright supersized. But is that always such a good thing? As it turns out, no. Size matters, but bigger is not always better for brains at least. When I was in high school, my biology teacher had us do the requisite frog dissection and offered extra …
When it comes to brains, bigger is not always better Read More »
What does the FDA define as “minimally manipulated” when it comes to biologics such as stem cells? You will be shocked to find out, but they include irradiation and treatment with the super toxin/carcinogen, ethylene oxide. In a recent post I discussed the issue of an apparent “minimal manipulation” exception (some might even call it a …
Why do people have such a big brain compared to other animals? Vertebrate embryonic development is a highly conserved process, particularly in the earliest phases. (note: you may find this September 2020 post on regulation of bee brain size to be interesting.) A wide variety of vertebrate animals including humans start out with embryonic body plans …
I’ve now been blogging about stem cells here on The Niche for nearly 2 years, but why do I keep doing it? I’m by no means the only one who blogs about stem cells, but it is just that professors still are reluctant in the stem cell field to blog. Two outstanding blogs that tied …
CIRM, the California stem cell agency, has funded hundreds of grants during its relatively short existence. You can do searches of these grants through a handy dandy web portal that CIRM has made available–it’s a very cool tool and I commend CIRM for making it available. I wish the tool had more options however including …
Word Cloud of Every CIRM-funded grant yields some surprising insights Read More »
Many of us have been discouraged by Geron’s decision to end their stem cell program, which included products based on human embryonic stem (ES) cells, but let’s keep some perspective on this and not give up hope. The opponents of hope want us to give up. They who have waged their own self-proclaimed war on …
Periodically we do updates on the iPS cell field and now seems like a good time. Where do things stand? Here’s my top 5 list of action items for the iPS cell field in the coming year. 5.) Methods on the brain. A significant fraction, some would argue too high a fraction, of iPS cell papers …
Periodically we do updates on the iPS cell field and now seems like a good time. Where do things stand? Here’s my top 5 list of action items for the iPS cell field in the coming year. 5.) Methods on the brain. A significant fraction, some would argue too high a fraction, of iPS cell …
Podcast for Week of July 5 Topics –Stem Cell Tourism in the U.S. –CIRM –Article in the Hill by stem cell opponent –Stem cell hype on aging Podcast for Week of July 11 Topics: –two papers on stem cell-based tissue engineering and one on stem cell treatments for heart disease, –the Republican candidates for …
Yamanaka may have found a way to give exogenous Myc the boot from the iPS cell universe. It has always been a frustration in the iPS cell field that Myc, a proto-oncogene, is so important for reprogramming. Yes, you can make iPS cells (especially mouse) without Myc, but it can be orders of magnitude harder, …