Two companies, Advanced Cell Technology (ACT) and Geron, both HQ’d here in California, have FDA-approved early stage clinical trials in the works. Geron’s trial has already started and reportedly now has enrolled at least two patients. The trial is of course for the safety of Geron’s GRNOPC1 oligodendrocyte product made from human ES cells for […]
Advanced Cell Technology and Geron: allies or competitors? Read More »
Yamanaka may have found a way to give exogenous Myc the boot from the iPS cell universe. It has always been a frustration in the iPS cell field that Myc, a proto-oncogene, is so important for reprogramming. Yes, you can make iPS cells (especially mouse) without Myc, but it can be orders of magnitude harder,
New iPS cell method: drop Myc or not yet? Read More »
I’ve been lecturing on stem cells as a professor here at UC Davis School of Medicine for many years so I can answer common questions such as “What are stem cells?”. The medical students ask many great questions. They are always interested in clinical applications. The goal of today’s article is to help you have
What are stem cells? Definition & what they are used for Read More »
There are a lot of myths in the stem cell field, some even embraced by some stem cell scientists such as the notion that teratoma are always benign. But when we start talking about translating stem cell technology into the clinic, to the bedside, it is especially important to cast aside our myths, no
Myth of Perfect Stem Cell: meaning for ACT, Geron and field Read More »
A Federal Appeals Court ruled 2-1 today to overturn Judge Lamberth’s injunction against federal funding of ES cell research. Great news! You can read the decision here (warning: big pdf). A key part of the ruling was the following: “the plaintiffs are unlikely to prevail because Dickey-Wicker is ambiguous and the NIH seems reasonably to
Victory for science and patients: what the appeals court ES cell ruling means (UPDATE) Read More »
What are iPS cells? We talk about iPS cells all the time. We are very excited about them. Heck, the web address for this blog is ipscell.com. But what are iPSCs, really? iPS cells definition A simple definition of iPSCs is the following: Embryonic stem cell-like cells that are made from non-stem cells in a
An insider’s guide: what are iPS cells? Read More »
The Oklahoma State Legislature is reportedly poised to potentially pass an outright ban of ES cell research. While in the past similar legislation was vetoed by previous Oklahoma Governor, Democrat Brad Henry, current Republican Governor Mary Fallin is likely to sign the legislation. The Oklahoman newspaper website today contains a factually incorrect, inflammatory piece by
Oklahoma leaders: ES cell research is not OK Read More »
It’s been more than 4 years since Shinya Yamanaka published the remarkable finding that his lab could transform or “reprogram” regular cells called fibroblasts into a very unique state that was quite similar to that of embryonic stem cells (ESC). Yamanaka called these new cells “iPS cells” for induced pluripotent stem cells. iPS cells Since
The Inside Scoop on iPS cells early in 2011 Read More »
Last Fall’s mid-term election brought into office several new Republican Governors who during their campaigns used strong, anti-embryonic stem (ES) cell research rhetoric. For example, then candidate for Governor of Wisconsin, Scott Walker (now the Governor) used some of the strongest language, which was ironic considering that human ES cells were first produced in Wisconsin
New Republican Governors Start Attack On Most Promising Stem Cell Research Read More »
In this post I give my most interesting predictions about events in the stem cell field in 2011. Update: I’ve continuing doing predictions every year all the way through 2020 and intend to continue. See my 2012-2020 predictions here. Appeals court rules in favor of federally funded hESC research. This is more of a hope
Predictions for Stem Cells in 2011 Read More »