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Interview with Jane Lebkowski on Asterias FDA-approved Stem Cell Trial

August 28, 2014 / Professor Paul Knoepfler, Ph.D. / 1 Comment

The BioTime subsidiary, Asterias, has received FDA approval for a combined Phase I/IIa clinical trial of OPC1 for treating spinal cord injury. BioTime (BTX) and Asterias (ASTY) have picked up the portfolio of the former Geron clinical trial using oligodendrocyte precursor cells (OPC). Asterias also acquired a second element from Geron in the form of a lung […]

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Interview with Ted Harada Part 2: Right To Try, Neuralstem, and How He’s Doing

August 24, 2014 / Professor Paul Knoepfler, Ph.D.

This is Part 2 of my interview with ALS and stem cell advocate, Ted Harada. You can read Part 1 of my talk with Ted on where things stand today with ALS, the FDA, and the Ice Bucket Challenge. What’s your opinion of the “Right To Try” law in Colorado and the concept more generally?

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Key questions for stem cell field bouncing around on a Friday morning

August 22, 2014 / Professor Paul Knoepfler, Ph.D. / 7 Comments

What are the most interesting questions for the stem cell field in 2014 right now? What’s on your mind? I’m not going to give this deep thought, but rather just list those questions bouncing around at the moment in no particular order. You can see a lot of translational/clinical things are on my mind. I’ve

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Ted Harada Interview Part 1: Stem Cells for ALS, More

August 21, 2014 / Professor Paul Knoepfler, Ph.D.

Ted Harada is a wonderful patient advocate for the stem cell field and for the development of safe and effective stem cell products to treat ALS. Ted has ALS and received stem cell-based treatments for it with surprising, very encouraging results. The Harada family is pictured at left with Ted, his wife Michelle as well as

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Has the FDA given up on regulating stem cell clinics?

August 8, 2014 / Professor Paul Knoepfler, Ph.D. / 14 Comments

What the heck happened to the FDA when it comes to regulating stem cell clinics? Has it given up? Or does it just seem that way because it moves in slow motion? The FDA might as well have thrown in the towel because, as I like to say, the stem cell field moves in dog years.

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Some cool recent stem cell papers: recommended reading

July 17, 2014 / Professor Paul Knoepfler, Ph.D. / 3 Comments

What have been some recent stem cell and/or regenerative medicine papers that are worth some extra thought and reading? There have been some cool ones. Note, for fun you can fast forward ahead to 2020 to see some of the recommended reads there. There was of course the very important Mitalipov group paper comparing NT

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StemCells, Inc. Faces Lawsuit With Serious Allegations

July 16, 2014 / Professor Paul Knoepfler, Ph.D. / 12 Comments

StemCells, Inc. is one of those stem cell-related biotech companies that we in the field hope will become a big success and help many patients in the future via stem cell technology. There are a lot of obstacles facing such companies. Some are privately held, while others such as StemCells, Inc. are publicly traded (stock

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Five possible natural stem cell boosts (but do your homework)

July 16, 2014 / Professor Paul Knoepfler, Ph.D. / 4 Comments

What might be some natural stem cell boosts? How might we all increase the number or helpful activities of our own stem cells? If possible isn’t that a better, simpler, & safer idea than getting a transplant of stem cells? Think of it as preventative medicine via stem cells. Note that this post was updated

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Duke Launches Large, Debated Stem Cells for Autism Trial

July 14, 2014 / Professor Paul Knoepfler, Ph.D. / 13 Comments

Is there real promise of stem cells for autism? At this point the jury remains out on that question, but a growing number of kids are nonetheless getting such “treatments” at for-profit dubious clinics. Academic clinical researchers are interested in this area as well. Still, the potential use of stem cells to treat autism is

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Woman grows nose tumor in spine after stem cell injection

July 8, 2014 / Professor Paul Knoepfler, Ph.D. / 5 Comments

Clare Wilson over at the NewScientist has reported the case of a woman given an experimental stem cell treatment in Portugal for a spinal cord injury who later developed a strange tumor consisting of nose tissue. I highly recommend going over to that site and reading her excellent article. What’s the deal with this case? The woman was

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