In the biomedical sciences we do a huge number of experiments on cells grown in culture including human cell lines. Where do all these cells come from? It’s an important question to ask. I got my first job in science as a fairly low level technician working at UCSD in La Jolla and my main […]
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Humans have big brains, right? In fact, they are downright supersized. But is that always such a good thing? As it turns out, no. Size matters, but bigger is not always better for brains at least. When I was in high school, my biology teacher had us do the requisite frog dissection and offered extra
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I confess. I have stem cells on the brain! Yeah, I probably have a few stem cells left in this old brain of mine, but that’s not what I mean….rather, I mean that I am really curious and excited about how stem cells do their jobs in our brains. More specifically, I wonder about things
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Why do people have such a big brain compared to other animals? Vertebrate embryonic development is a highly conserved process, particularly in the earliest phases. (note: you may find this September 2020 post on regulation of bee brain size to be interesting.) A wide variety of vertebrate animals including humans start out with embryonic body plans
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Interestingly, the Komen Foundation appears open to funding human embryonic stem cell (hESC) research. The latest report from Science includes a quote from Komen that denies any changes in funding policy for research and suggests they have not ruled out funding such research: Contrary to circulating online reports, Komen has not “de-funded” any grantee based on human embryonic stem
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Federal funding of human embryonic stem cell (hESC) research is hanging by a tenuous thread at the moment. While currently legal, such funding is at the mercy of a legal case making its way through the courts. The latest stop for this case is a review by a 3-judge panel of the DC Circuit Court.
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I have in the past posted advice to new faculty and also top 10 advice list for the academic job hunt, but today I wanted to specifically talk about mentoring. Also, stay tuned for a special post later this week with an autobiographical section from Irv Weissman on his early career and who his key
How to find and be a good mentor? Read More »
Our focus in this podcast is more on hard core stem cell and regenerative medicine science, and includes my choice for the paper of the week. –human neural stem cells aid recovery from brain irradiation of the kind used to treat brain cancer –paper of the week: transdifferentiation of fibroblasts to make functional neurons using
This Week in Stem Cells With Dr K., Episode 3 Read More »
Podcast for Week of July 5 Topics –Stem Cell Tourism in the U.S. –CIRM –Article in the Hill by stem cell opponent –Stem cell hype on aging Podcast for Week of July 11 Topics: –two papers on stem cell-based tissue engineering and one on stem cell treatments for heart disease, –the Republican candidates for
What are iPS cells? We talk about iPS cells all the time. We are very excited about them. Heck, the web address for this blog is ipscell.com. But what are iPS cells, really? A simple definition of iPS cells is the following: Embryonic stem cell-like cells that are made from non-stem cells in a lab.
An insider’s guide: what are iPS cells? Read More »