Search Results for: crispr

Recommended reads: private cord blood bank disappointments, Mammoth genomes, Huntington’s CRISPR, Parkinson’s cell therapy

umbilical-cord-blood, umbilical cord blood stem cells

The private cord blood bank industry has promised families all kinds of great things over the years. A typical ad for such cord blood banks might say, “Your child may need cord blood in the future for a cure.” The industry also often uses the analogy of frozen cord blood as an insurance policy for […]

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Recommended reads: flesh-faced robots, ALS, Spina Bifida,neuronal CRISPR

flesh-faced robots

Combinations of human flesh and robots are more in the news lately. Sometimes the fleshy parts are grown from stem cells in a lab. Robots with fleshy faces Scientists in Japan Give Robots a Fleshy Face and a Smile, NYT. I’m working on a piece about robots in China with small, human brain-like structures. Stay tuned

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Recommended reads: CAR-T for Lupus, CRISPR vision, journal closures

CAR-T for Lupus

Can researchers use CAR-T for lupus? It’s always exciting when one’s home institution has an interesting new therapy in development.  Here at UC Davis Health, there has been an increasing stream of such encouraging trials in the pipeline. I’ve written before about the promising trial of stem cells for spina bifida. Now there’s news related

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Weekly reads: Vertex & CRISPR Therapeutics, Arnold Caplan death, MS genetics

CRISPR Therapeutics

The biotechs Vertex and CRISPR Therapeutics have an interesting relationship as biotechs. They are partners are multiple levels but also are very different as companies including in size. There’s been a key development in one of their partnerships. Before we jump into that, please check out the video version of my 20 stem cell and

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Weekly reads: new Sergiu Pasca pub, CRISPR chicken, human gene count update, stem cells in China

Sergiu Pasca, assembloid

Most of us have heard of organoids but what about the related model called an “assembloid”, which is a term growing in use including from organoid researcher Sergiu Pasca of Stanford? Before we jump into that, be sure to enter The Niche stem cell image contest for your chance to win $100 or some swag.

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Weekly reads: CRISPR sickle cell, Parkinson’s, pig-human chimera concerns

CRISPR gene editing

CRISPR gene editing has made rapid progress heading from bench to bedside. Perhaps the fastest has been its progress toward clinical use to combat sickle cell disease. We’ll start with a new paper on one major effort here. CRISPR gene editing. This process often involves cutting DNA, which then can be used as an opening to

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Weekly reads: Vertex stem cells for diabetes update, new CRISPR , immortality

stem cell therapy for diabetes

Where do things stand with the investigative approach of stem cells for diabetes? 33% of Type 1 Diabetes Patients Insulin-Free With Stem Cells, Medscape. Not the best headline given the few number of participants here. If your study has only two subjects and one responds, someone is going to say, “50% of people had a

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Weekly reads: gene therapy nod, Nature pub ethics, CRISPR LDL

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Totipotency literally means all powerful, but it refers in biology to specific cells. These cells can make every type of cell in the body of an organism plus the extraembryonic tissues needed for development. This includes humans. So if you could reprogram human cells like blood or skin cells into totipotent stem cells, you might

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Weekly reads: UC Davis Medical School diversity, CRISPR, Parkinson’s

UC Davis Medical School

It’s been almost seventeen years that I’ve been a professor here at UC Davis Medical School. It feels like home. I enjoy teaching our first-year medical students each year. Some end up doing research in my lab. Our school recently got a nice write-up over at STAT News by Usha Lee McFarling on the diversity

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Weekly reads: big CRISPR mtg, Mesoblast good news, Neuralink spiked

Victoria Gray, CRISPR meeting

Where do things stand with potential applications of CRISPR and other gene editing technologies in patients? Overall, things are looking very positive. CRISPR human trials This week the third big international human genome editing meeting took place in London. The summit addressed numerous potential clinical applications. It was good to see the agenda included quite

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