Search Results for: crispr

Mosquitoes swat back via resistance to CRISPR gene drive

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What’s more worrisome, potential disease-carrying mosquitoes or releasing self-perpetuating CRISPR gene drive out into the wide world to combat them? We know how the mosquitoes would answer that question, right? And they are fighting back, in a sense, at least in the context of experiments. Mosquitoes were able to develop resistance to gene drive intended

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Interview with Fredrik Lanner who is CRISPR’ing healthy human embryos

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In the past year there has been a great deal of attention given to the potential use of CRISPR-Cas9 for gene editing in human embryos. An important recent development, described in a new NPR article by Rob Stein, is the use of CRISPR-Cas9 in healthy human embryos for developmental biology research by assistant professor Fredrik

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Where are all the new CRISPR human embryo papers?

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Last year I heard from several sources that there somewhere between 3-5 unpublished manuscripts reporting the use of CRISPR gene targeting in human embryos being shopped around at various journals in addition to the one that had been published. Since that time we’ve seen a grand total of one additional paper reporting on CRISPR of human

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Gaetan Burgio New Data & Theory on NgAgo versus CRISPR

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By Gaetan Burgio CRISPR/Cas9 genome editing has dramatically changed our way to perform biological experiments. While highly efficient and easy to use, one limitation with CRISPR/Cas9 mediated genome editing technology is the occurrence of off-target effects and the restriction of the PAM recognition sequence. Many modifications from the original system have been proposed to improve

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Controversy over CRISPR challenger NgAgo irreproducibility reported

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Does the new gene editing method NgAgo work or not? If not, what happened? The answers to both questions seem to depend on who you ask and what you read. As much as CRISPR has been the revolutionary in the genetic modification technology arena over past methods, could CRISPR itself in the next few years

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