What’s more worrisome, potential disease-carrying mosquitoes or releasing self-perpetuating CRISPR gene drive out into the wide world to combat them? We know how the mosquitoes would answer that question, right? And they are fighting back, in a sense, at least in the context of experiments. Mosquitoes were able to develop resistance to gene drive intended […]
Mosquitoes swat back via resistance to CRISPR gene drive Read More »
I got a package from my publisher and upon opening it I saw the Korean edition of my book GMO Sapiens on the potential use of CRISPR in humans. The English language edition can be purchased here at the publisher where you can get 35% using the discount code WS16XMAS35 until January 15th or here on Amazon.
Korean edition of my GMO book on human CRISPR is out Read More »
In the past year there has been a great deal of attention given to the potential use of CRISPR-Cas9 for gene editing in human embryos. An important recent development, described in a new NPR article by Rob Stein, is the use of CRISPR-Cas9 in healthy human embryos for developmental biology research by assistant professor Fredrik
Interview with Fredrik Lanner who is CRISPR’ing healthy human embryos Read More »
Last year I heard from several sources that there somewhere between 3-5 unpublished manuscripts reporting the use of CRISPR gene targeting in human embryos being shopped around at various journals in addition to the one that had been published. Since that time we’ve seen a grand total of one additional paper reporting on CRISPR of human
Where are all the new CRISPR human embryo papers? Read More »
By Gaetan Burgio CRISPR/Cas9 genome editing has dramatically changed our way to perform biological experiments. While highly efficient and easy to use, one limitation with CRISPR/Cas9 mediated genome editing technology is the occurrence of off-target effects and the restriction of the PAM recognition sequence. Many modifications from the original system have been proposed to improve
Gaetan Burgio New Data & Theory on NgAgo versus CRISPR Read More »
Will NgAgo strongly challenge CRISPR in coming years? Take our poll and also see the results to find out what others thought. 2020 update: NgoAgo has ending up going nowhere, but 4 years ago we didn’t know that would be it’s fate although some of us were skeptical early on.
Poll: Will NgAgo strongly challenge CRISPR in coming years? Read More »
Does the new gene editing method NgAgo work or not? If not, what happened? The answers to both questions seem to depend on who you ask and what you read. As much as CRISPR has been the revolutionary in the genetic modification technology arena over past methods, could CRISPR itself in the next few years
Controversy over CRISPR challenger NgAgo irreproducibility reported Read More »
Want $250 as well as at least a sliver of science-related glory? Within my new book GMO Sapiens on CRISPR and human genetic modification, I’ve hidden a scientific Easter egg. There’s more Easter egg info over here including the rules. If you are the first one to find and properly explain this egg to me after buying
Hint for $250 Easter egg in GMO Sapiens #CRISPR book Read More »
Science hype deserves negative attention for the harm it does including both to science itself and to patients. I’ve seen two really egregious examples of hype lately in science headlines. First from the Washington Post comes a stem cell story with a very hype-ful title: Stanford researchers ‘stunned’ by stem cell experiment that helped stroke
2 Recent Science Hype Awards on CRISPR & Stem Cells Read More »
