I’ve written extensively about the potential use of CRISPR in humans, including in particular in the germline where it would lead to heritable genetic modifications. Research using CRISPR in human embryos strictly for research purposes (not reproduction) is proceeding and in the case of non-viable embryos, such work has already been published (e.g. here), but […]
Human CRISPR TED talk Read More »
Now we hear from the scientists on the front lines of CRISPR, covered in this post #2 of the Human Gene Editing Meeting. You can read Post #1 here. Jennifer Doudna starts off the big human gene editing science session on the current state of the human gene editing science and CRISPR. She gave an
Live Blogging #GeneEditSummit Day 1 Post #2: State of the Science, #CRISPR Read More »
A recent piece on CRISPR genetic modification in the New Yorker called The Gene Hackers or Human 2.0 by Michael Specter is striking in a number of ways. I highly recommend it. The article provides an in-depth look at CRISPR and its potential use for human editing. I like how the article brings so many
Haunting Doudna nightmare about Hitler wanting CRISPR Read More »
I always like to do a bunch of science reading on the weekend when it’s quiet including stem cells, but also many other areas such as brain tumors and more. Here are some TGIF science links to thought-provoking reading. CRISPR stuff Where in the world could the first CRISPR baby be
TGIF science links: CRISPR, stem cells, caffeine, & more Read More »
I just did a blog post today on the striking story of someone doing DIY CRISPR gene therapy on themselves. A question came to mind. How long until someone does a DIY attempt to CRISPR themselves? In the DIY gene therapy story, the person was injected with so-called “gain-of-function” viruses to try to reap health
Tick Tock Genetic Clock: How soon until first DIY CRISPR of self? Read More »
Google is reportedly getting into the genetic modification business. It plans to use a sexy, new genetic technology called “gene drive”, which has both excited and unsettled scientists due to its great power to make GMOs in nature via reproductive chain reactions. This move toward genetic modification is part of a larger trend of Google
With CRISPR, is GMO also for Google? Read More »
In a poll on CRISPR, respondents so far have predominantly viewed potential off-target effects as a moderate (28%) to substantial (25%) problem. The poll is still running if you are interested in participating. As to the more polar answers, only 20% and 4% answered “minor” or “a non-issue”, respectively, while 14% thought that off-target effects
CRISPR off-target effects important, but not severe challenge, says poll Read More »
Professor Steven Pinker of Harvard has been making the case recently that when it comes to novel biotechnologies such as CRISPR-Cas9 that bioethics should just get out of the way. Further, he has argued that we do not need a moratorium on clinical use of CRISPR-Cas9 for human genetic modification. In fact, he says that
Why I Disagree with Steven Pinker On CRISPR Read More »
Scientists studying genetics are both excited and worried about a powerful, new technology called “gene drive“. Some have been raising serious concerns about gene drive and in certain cases calling for proactive regulation, which is unusual in science. This method is so powerful because it is designed to induce genetic changes in an entire population
Exciting CRISPR-powered “gene drive” also has scientists deeply concerned Read More »
CRISPR-Cas9 gene editing technology is red-hot right now and I’ve been doing interviews with various thought leaders on it, which today includes Steven Pinker. This technology has great power for research in the lab and there are hypothetical transformative clinical applications of CRISPR too. The latter efforts could include experimental attempts at reversal of disease-causing
Steven Pinker interview: case against bioethocrats & CRISPR germline ban Read More »