Search Results for: crispr

Live blogging Future of Genome Medicine: great talks by Feng Zhang & others

Feng-Zhang-talk-e1488664593428

What is the future of Genome Medicine? The meeting by that same name that I’m at down here in La Jolla is all about tackling this question and the line up of speakers today on the first day is amazing. I’m speaking about IPS cells as a basis for personalized medicine tomorrow morning so that’s exciting. […]

Live blogging Future of Genome Medicine: great talks by Feng Zhang & others Read More »

Q&A video with Paul Episode 1: your stem cell questions answered

Where is the stem cell field now and where the heck is it heading? There are hundreds of questions. Readers often email me questions or leave them as comments. It’s not unusual to get questions about CRISPR as well. As time permits, I’m hoping once or twice a month on Sundays to post a video answering

Q&A video with Paul Episode 1: your stem cell questions answered Read More »

National Academies panel leaves door a crack open to future human genetic modification

Early-human-embryos

A National Academies panel on human genome editing chaired by Alta Charo and Richard Hynes released its report today. While it covered both somatic and germline (heritable) human genetic modification, the latter topic is far more contentious. You can see the National Academies summary of their report here. You can read the full report here.

National Academies panel leaves door a crack open to future human genetic modification Read More »

Perspectives on pig human chimera paper

human-pig-chimera

A new paper focused on human and other chimeras just came out today in Cell reporting a number of findings, but most strikingly successful generation of human-pig chimeras in utero. The paper, entitled, “Interspecies Chimerism with Mammalian Pluripotent Stem Cells” describes various chimeras including mouse-rat ones, although those have previously been reported. This work comes

Perspectives on pig human chimera paper Read More »

First 3-person IVF baby born via “rogue” experiment at Mexico clinic?

John-Zhang-with-3-person-IVF-baby

Today we got the first report of a baby being born via so-called “3-person IVF”, sometimes called 3-parent IVF, in which the DNA of three people contribute to an offspring. Before discussing this further I have to emphasize that we need proof that this is indeed really a 3-person IVF baby via genetic testing. Until that

First 3-person IVF baby born via “rogue” experiment at Mexico clinic? Read More »

Nature Biotechnology looking at NgAgo paper amidst reproducibility concerns

NgAgo-China-newspaper

When potentially game changing new technologies are reported such as NgAgo gene editing, both scientists and the public get excited, but especially if such new reports stem from a single paper it is wise to take a cautious approach for a while. The key question is whether the new findings will turn out to be

Nature Biotechnology looking at NgAgo paper amidst reproducibility concerns Read More »