This guest piece on Human Germline Genetic Modification is by Lisa C. Ikemoto, Professor, U.C. Davis School of Law. I have been following the reports about genetic editing technology with concern. The fact that some scientists are calling for moratoria on gene editing of human embryos heartens me. Frankly, I had little confidence that any […]
Lisa Ikemoto on Human Germline Genetic Modification Read More »
CRISPR Cas9 gene editing technology is a game changer on many levels both inside and soon outside the lab. There is a growing sense of urgency amongst biomedical scientists to take a proactive approach to current and future use of CRISPR gene editing technology in human germ cells and embryos. These concerns have been heightened
Practical Plan for Managing Human Germline CRISPR Read More »
In a new perspectives piece in Science, Nobel Laureate David Baltimore and co-authors including Jennifer Doudna and George Church, chart a potential path forward for human germline engineering. See also accompanying Bioethics piece by Gretchen Vogel as well, “Embryo engineering alarm”. In the piece, entitled “A prudent path forward for genomic engineering and germline gene
David Baltimore, et al. path for human germline engineering Read More »
The International Society for Stem Cell Research (ISSCR) just now released a new policy statement on human germline gene editing. The statement calls for a ban on clinical application of human germline gene editing technology. Here is the brief summary statement at the beginning: The International Society for Stem Cell Research calls for a moratorium on
The field recently saw Lanphier, et al. in Nature calling for a moratorium on human germilne CRISPR genetic modification. A number of additional stakeholders are expected to be weighing in soon on the issue of human germline gene editing. For example, a Science paper from others in the gene editing community is anticipated soon and may well have somewhat different perspectives. I’ve been
Intensifying dialogue on human germline gene editing Read More »
When you go into the bathroom, you might expect to see graffiti on the wall, right? I recently saw something very different that left me surprised. Around Sacramento a new kind of “writing on the wall” is showing up in some bathrooms in the form of essentially a paper advertisement taped to the stall wall
Ad In Bathroom Stall: Your Stool Needed as Life-Saving Tool Read More »
You might enjoy the recommended reads below and find they surprise and educate you. Products in the pipeline – Ocata’s RPE by Alexey, a nice update on Ocata. Yes, we are seeing more attacks on academic freedom: guest post by historian of science and medicine. Guest piece by Alice Dreger on her new book, Galileo’s Middle Finger.
Weekend Reads from a Wild, Fun Week of Science Read More »
Today I’m posting about pet peeves in the science lab. Who doesn’t have some of those? And, yeah, we are all probably guilty at one time or another of driving other people a bit nuts with our own idiosyncrasies that are their pet peeves. This post is another in my “Elephant in the Lab” series about difficult, but important
Ten lab pet peeves: elephant in the lab series Read More »
I recently interviewed leading genomics scientist George Church on the ways that trends in genomics are changing our world. We also discussed the possibility of heritable human genetic modification. These days we more often call this “CRISPR babies.” His answers suggest that genomics and gene editing are poised to radically change our world. They could literally
George Church on Germline Human Genetic Modification Read More »
Here are some papers and news for weekend reads. What are you reading this weekend? What are your go-to stem cell journals? Hostile Takeover: Glioma Stem Cells Recruit TAMs to Support Tumor Progression by Yu Shi, Yi-fang Ping, Xia Zhang, Xiu-wu Bian in Cell Stem Cell. YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate self-renewal and
Weekend Reads: Cool Papers, PubPeer, Jacob Hanna, & More Read More »