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Interview with NIGMS Director, Jeremy Berg, part 1: grant advice, meritocracy

September 17, 2012 / Professor Paul Knoepfler, Ph.D.

Obtaining research grant funding is a critical part of science, but the process seems to be getting more challenging each year. Funding rates are decreasing. Applicant frustration is increasing and many grant applicants tell me they feel confused about the differences between funded and unfunded proposals. The largest funder of biomedical research in the U.S. […]

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My collection of funny signs: UFO lemonade & falling coconuts

September 15, 2012 / Professor Paul Knoepfler, Ph.D.

I live in Davis, CA. Sometimes it seems like Davis is a bubble full of the most colorful assortment of characters. One day walking my dog Elvis I noticed the sign to the right. I translated it as “Shh”. I’ve seen many signs in my days, but never one like this…it seems a little too

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NIH grant process is painful on many levels according to poll respondents

September 14, 2012 / Professor Paul Knoepfler, Ph.D.

I started a poll on what PIs dislike most about the NIH grant process. Why did I even do such a poll? I’ve been a professor for 6 years now and even in just a half a dozen years it’s clear that the grant process has become more and more painful. The poll results suggest

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Alienable: how personifying corporations & zygotes robs real people of their rights

September 13, 2012 / Professor Paul Knoepfler, Ph.D. / 2 Comments

In the U.S. Declaration of Independence three “inalienable rights” are said to be endowed on people: life, liberty, and the pursuit of happiness. People also have other rights in the U.S. including freedom of speech and religion. These rights seem clear enough, but wait a minute….what are “people”? What entity qualifies as a “person” to

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Bionic eye here at UC Davis holds great promise for restoring vision

September 12, 2012 / Professor Paul Knoepfler, Ph.D.

I love stem cells, but I have to admit bionics is totally amazing as well. Both hold great promise for fixing up human beings as we injured or age. Today a major advance in vision correction via bionics was announced here at UC Davis that has really caught my attention. I was not involved in

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L’Oreal Lancome gets hammered by FDA, why kid gloves for clinics?

September 11, 2012 / Professor Paul Knoepfler, Ph.D. / 7 Comments

Stem cell cosmetics is an exploding area ranging from facial creams (e.g. from L’Oreal and its Lancome) to face lifts to boob jobs to baldness treatments (see two key posts here and here for background and great stories). The stem cell cosmetics field has not been held back by issues such as the fact that

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Funny Mitt Romney as Game Show Host Poll: which show would be his?

September 10, 2012 / Professor Paul Knoepfler, Ph.D.

I watched Mitt Romney on Meet The Press a bit on Sunday morning. I’ve of course seen him other times interviewed on TV. I keep thinking to myself “Who is the real Mitt Romney?” One thought was that he reminded me of a game show host! Somehow that fits. Then I thought of the game

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Real and imaginary conflicts of interest: a helpful guide

September 4, 2012 / Professor Paul Knoepfler, Ph.D. / 4 Comments

Conflicts-of-interest-creative-commons-image

What are Conflict of Interests (COI)? The term COI is sometimes used inappropriately as a weapon by one party to attempt to discredit others. We see this more and more frequently in the stem cell field with boosters of for-profit, non-FDA vetted adult stem cell clinics attacking scientists for supposed COIs for what…..apparently for simply

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The good, the bad, and the ugly of the Republican Convention

August 31, 2012 / Professor Paul Knoepfler, Ph.D. / 3 Comments

I watched some parts of the big speeches at this year’s Republican Convention in Tampa and was struck by a number of things running the gamut from good to bad to ugly. I think Mrs. Romney did a good job on her speech. She came across as likable and someone I can imagine as a

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Caloric restriction: dieting monkeys teach human scientists?

August 30, 2012 / Professor Paul Knoepfler, Ph.D. / 7 Comments

The notion of caloric restriction (CR) as a means to prolong human life is intriguing. The basic idea of CR is that if you eat a lot less than the average person you’ll live longer. You might even live a higher quality, healthier life. But is this true? (update: see my newer post on 5

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