Yesterday at ISSCR 2016, Fiona Watt gave a great talk about plasticity of epidermal stem cells. As with my other #ISSCR2016 posts, this one is a stream of impressions, quotes, and key points. For my other blog posts from the meeting see here. First she provided a nice overview of human skin architecture and regulation. The …
Fiona Watt excellent talk on epidermal stem cell plasticity #ISSCR2016 Read More »
Our entire world is full of plastics these days to the point that we ourselves are now partially made of plastic literally. When you hear someone say that another person is so “plastic”, slang meaning artificial, these days it is kind of literally true, but for all of us. Even the seemingly infinite oceans of …
Last week one of the most popular stories was about a preprint from a mammoth de-extinction research group led by George Church having made elephant stem cells. I finally got a chance to look carefully at their preprint. Elephant stem cells preprint and mammoth de-extinction The elephant stem cells preprint has solid data. It looks like …
Weekly reads: elephant stem cells, RIP Connie Eaves, AI cell biology Read More »
Paolo Macchiarini is one of a small group of people in the stem cell universe whose misconduct has blown up in the press. Piero Anversa, Haruko Obokata, Hwang Woo-Suk, and some operators in the unproven stem cell clinic sphere come to mind. Macchiarini published quite a few seriously problematic papers, some of which just hung …
Weekly reads: late Macchiarini retractions, stem cells & Lululemon Read More »
Who is David Sinclair and why is he all over the media related to anti-aging efforts? This post is my effort to fact-check Sinclair’s statements in the context of the broader rejuvenation arena. In the process I also review his most recent paper from my view as a stem cell and cancer biologist interested in …
Review of new David Sinclair paper, supplements & anti-aging glitz Read More »
With the pandemic still here but less severe there are more in-person conference opportunities including stem cell meetings. It seems certain that moving forward though that there will be far more virtual opportunities too. That’s a good thing. You can see last year’s stem cell & regenerative medicine meetings 2022 page too. 2023 stem cell …
Hub of regenerative medicine & stem cell meetings 2023 Read More »
I get great questions from readers of The Niche including, “Are there multiple ways to get stem cells?” The answer is “yes.” Why is this important? The different sources of stem cells can impact both their use in basic research and their potential clinically. My goal in today’s post is to give an overview of …
Digging into the multiple ways to get stem cells Read More »
It’s always great to read about stem cell clinical trials that are looking encouraging. Stem cell clinical trials Proving a new therapy is safe and effective is so challenging. Remarkably, there are more than 9,300 stem cell clinical trials listed for a “stem cell” search on Clinicaltrials.gov. Of course, not all of these are actual …
I’m fascinated by the idea of making food from cells grown in a lab and especially the newest idea of lab-grown chocolate. While lab-grown meat has gotten the most attention, (see my recent post on test-tube meat: Not Old MacDonald’s Farm: is the future lab-grown meat?) I’d say that the coolest application of making food from …
Biotech California Cultured aims to sell lab-grown chocolate Read More »
Stem cell research relies on some unusual reagents at times including a cell culture product called Matrigel. One of the challenges with such reagents is that if they suddenly are back-ordered it could bring some research to a halt. Matrigel has been in short supply for the last year or so. These products also tend …
What is Matrigel, why a shortage, & alternatives? Read More »