Search Results for: pluripotent stem cells

Multipotent & totipotent vs pluripotent stem cells

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

What’s the difference between multipotent stem cells, totipotent stem cells, and pluripotent stem cells? The goal of today’s post is to help you learn and be clear on the differences. What’s in this article Definition of stem cells |Totipotent vs pluripotent stem cells | Pluripotent stem cells | Multipotent stem cells | The best kind of stem …

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Recommended reads: pluripotent stem cells, neural crest, cancer, more

pluripotent stem cell, neural crest cells

There has been quite a lot of pubs on research on pluripotent stem cells published lately. These include some more surprising findings such as a potential role for pluripotency-related programming in neural crest development. Here the week’s recommended reads. Neural Crest research: ties to factors involved in pluripotent stem cells Science, Reactivation of the pluripotency …

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What are induced pluripotent stem cells or IPS cells & clinical prospects?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or IPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too, both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as drug screening. The …

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Mutations in pluripotent stem cells: No, the sky is not falling

Figure-3-Merkle-et-al.-e1493736482727

By Jeanne Loring “Mutation” and “cancer” are eye-catching words for a headline; add “stem cells” and there is a good chance that a lot of people will hear about it. These words have been liberally used in the press to describe the results of a recent publication: “Human pluripotent stem cells recurrently acquire and expand …

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Is REGROW Act anti-embryo research? Pluripotent stem cells excluded

REGROW-Act

The REGROW Act has attracted both support and criticism, including on this blog, for the changes it would mandate in the way the FDA regulates stem cell products. More specifically it would greatly reduce regulation of experimental stem cell products. I believe that would be dangerous to patients and to the stem cell field more …

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If I only had a brain: brain organoids from pluripotent stem cells

In a first for the field, scientists have used human pluripotent stem cells to grow miniature brain-like structures (brain organoids) in a dish in a lab (see beautiful image of one of these “mini-brains” at left from the paper). This exciting, pioneering feat, accomplished by a team from the Austrian Academy of Science in Vienna …

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Jury is still out on purported adult pluripotent stem cells despite new MUSE paper

MUSE-cells

Are MUSE cells for real? Stem cells come in different types that vary in a key property called “potency”, but very few are pluripotent. The more potency, the greater the flexibility of a stem cell to make other cell types. Flexibility in the cellular world is power. The most powerful stem cells generally used are …

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iPS cells top poll as most clinically promising pluripotent stem cells

I just closed my blog’s poll on what are the most clinically promising pluripotent stem cells. Why close the poll now less than 12 hours after I opened it instead of leaving the poll open longer? You’ll find out soon enough. I can’t resist teasing you readers sometimes. iPS cells were the big winners in …

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Why Yamanaka deserved the Nobel Prize for induced pluripotent stem cells

I believe and have argued for years that Shinya Yamanaka, the discoverer of induced pluripotent stem cells (aka iPS cells) deserves the Nobel Prize. I’m very glad today that he received it. Some readers may find it a bit ironic that I believe so strongly in this way since over the years I have often …

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Fact-check of stem cell therapy for pain & neuropathy

knoepfler turner cell stem cell 2016 fig. 2b stem cells for pain and other conditions

Does it make any sense medically or scientifically to use stem cell therapy for pain or neuropathy? There isn’t much solid evidence that this is a good way to go. However, there’s a vast scope of research ongoing in this area. Stem cell clinics have been earning millions of dollars each year selling this idea …

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