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Patient’s Powerful Story on Multiple sclerosis and Getting Experimental Stem Cells

April 2, 2018 / Professor Paul Knoepfler, Ph.D. / 16 Comments

Multiple sclerosis (MS) can be an extremely debilitating disease that ultimately is fatal in some patients and reduces life expectancy and quality overall substantially. An MS patient named Caroline Wyatt, who works at the BBC, had the courage to open up in full detail on the BBC about having MS, her experience getting an experimental […]

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Stem cell good news on biotechs & cool new organoid paper

March 28, 2018 / Professor Paul Knoepfler, Ph.D. / 3 Comments

There’s some recent stem cell good news out there including new papers and biotech developments. The stem cell and regenerative medicine field is really diverse and runs the gamut from really worrying stuff to very exciting, legit developments. In this post, I’m going to focus on the encouraging recent developments. What do I see as

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Bigger picture study casts big doubts on stem cells for knee arthritis today

March 26, 2018 / Professor Paul Knoepfler, Ph.D. / 34 Comments

Knee arthritis, stem cell therapy for knees

One of the most common claims made by unproven, for-profit stem cell clinics is that the stem cells they are selling can help knee arthritis and associated pain, but what is the evidence to back this up? There are many problems with the claims of stem cells for arthritis being made across the U.S. In

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Grading 3 stem cell media reports on clinical science: vision, MS, & paralysis

March 21, 2018 / Professor Paul Knoepfler, Ph.D. / 9 Comments

Rosenzweig-et-al-Nature-Medicine-2018-part-of-Fig.-1

What is stem cell media? When us scientists hear the phrase “stem cell media” we usually think about the liquid food that we feed our stem cells in the lab, which resembles a kind of nutrient-rich Kool-aid, but another kind of stem cell media consists of the news coverage of stem cells. This other kind

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Stem cell weekend reads & science headlines

March 17, 2018 / Professor Paul Knoepfler, Ph.D.

Leeman-et-al.-Science-2018-part-of-Figure-1a

Here are my suggested weekend reads on stem cells & regenerative medicine. I also threw in some stem cell news headlines and more general science stories…and some CRISPR. What are your weekend reads? Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging in Science (a.k.a., taking out the stem cellular trash for

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What should we call “stem cell clinics” & is “snake oil” too harsh for some?

March 15, 2018 / Professor Paul Knoepfler, Ph.D. / 17 Comments

Is “snake oil” too harsh a term for some of what is sold at some of the worst stem cell clinics? Is the phrase “stem cell clinics” itself accurate and useful in a broad sense? When we read or write the phrase “stem cell clinics”, most people generally know what we’re talking about, but it

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Take-homes from new FDA NEJM stem cell piece including surprises

March 8, 2018 / Professor Paul Knoepfler, Ph.D. / 5 Comments

FDA Commissioner Scott Gottlieb and CBER Director, Peter Marks, have just published a new piece on stem cells and regenerative medicine in the New England Journal of Medicine (NEJM). What are the core points here and what can we learn from reading between the lines a bit? There are some expected things and then some

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Stem cell penile growth fact check

March 4, 2018 / Professor Paul Knoepfler, Ph.D. / 5 Comments

Ben-Greenfield-stem-cell-penis-injection

When I read about a stem cell penis growth injection, what comes to mind first when you read that is “Ow!” The goal of today’s post is to fact-check this whole area. What’s in this article Stem cell penis growth | Risks |US Stem Cell Clinic claims |Does it work? | Does size matter? | Data check

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Popping the bubble of stem cell populism

February 25, 2018 / Professor Paul Knoepfler, Ph.D. / 11 Comments

What happens if we mix stem cells with populism? From a populist view of stem cells, everyday patients should be able to do nearly anything they want with stem cells without any governmental interference or excessive expense. Even stem cells not proven to be safe or effective. This can sound like an appealing idea to

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TGIF: Guns, stem cells, science weekends reads & good news

February 16, 2018 / Professor Paul Knoepfler, Ph.D.

Wakabayashi-et-al.-Cell-Stem-Cell-Figure-1F

I’ve got some TGIF recommend reads on stem cells, etc, but first, what a week, right? We need more action on preventing gun violence. It’s a uniquely American health crisis that doesn’t have to be. There’s no real, common sense reason that gun control can’t reduce mass killings of our kids and others like the

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