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Suit against Dr. Alvaro Skupin & Dra Nancy Alvarez over blinding at clinic is settled

September 14, 2023 / Professor Paul Knoepfler, Ph.D. / 2 Comments

A patient who got scientifically unproven and non-FDA-approved stem cells from Dr. Alvaro Skupin, filed suited against him, his wife who is often known as Doctora Nancy or Dra Nancy Alvarez, and associated businesses. These firms include the stem cell clinic known as Mother Stem Cell Institute in Florida, where the injections apparently took place. […]

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Strangest things I’ve seen & heard in research lab

September 12, 2023 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Being in a research lab feels like hanging out in a second home to me. Maybe that’s because I’ve spent more than half of my life working in labs. Being a scientist has its challenges. However, at times it’s very exciting such as when a discovery is made. The lab can kind of buzz with

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Vivek Ramaswamy & his surprising stem cell start

September 5, 2023 / Professor Paul Knoepfler, Ph.D. / 3 Comments

Many of us first became aware of Vivek Ramaswamy as a Republican candidate for President. He was most well-known before that as a biotech leader. Given that biotech background, I decided to learn more about him. Surprisingly, his biomedical efforts may have started with embryonic stem cells. That caught my attention. This was way back

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Weekly stem cell reads: Google Bard AI issues, fat ball reprogramming, BrainStorm on ALS

July 30, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

It’s great finding stem cell videos on YouTube that are either excellent research talks or provide important information. I recently found one such video by Shiri Gur-Cohen, which I included below. Interesting data there and Shiri is such a compelling speaker. She also won The Niche image contest one year with a cool microscopy pic

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Review of new David Sinclair paper, supplements & anti-aging glitz

July 18, 2023 / Professor Paul Knoepfler, Ph.D. / 8 Comments

Who is David Sinclair and why is he all over the media related to anti-aging efforts? This post is my effort to fact-check Sinclair’s statements in the context of the broader rejuvenation arena. In the process I also review his most recent paper from my view as a stem cell and cancer biologist interested in

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Stem cell therapy cost in 2024: data & analysis

June 15, 2023 / Professor Paul Knoepfler, Ph.D. / 4 Comments

How much does stem cell therapy cost in 2024? How have prices changed? To authoritatively answer these questions now we need data from the present and past along with expert perspectives. Some surprises come up in this new analysis. In this article Intro | Stem Cell Therapy Cost: $10,000-$20,000 | Why do stem cells cost so much?

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Weekly reads: stem cell for hair loss, clinic lawsuit update, 2 big retractions

June 11, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

There seems to be a never-ending supply of stem cell for hair loss research but a new article invokes a novel mechanism. Stem cell for hair loss research and cell mechanics Here’s a recent news item about a PNAS paper: Coaxing hair growth in aging hair follicle stem cells, NW Now. A common theme is things

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Weekly reads: FDA nod on new cell therapy, gray hair, pong-playing cells

April 23, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

It’s a big challenge to get a cell therapy approved by the FDA and if you look at my list of FDA-approved stem cell therapies, it’s not as long as we might hope. FDA OK on cell therapy from Gamida Cell For this reason, it was excellent news to see that the FDA approved a

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WHYY oh WHYY: NPR puff piece on risky stem cell microneedling

March 14, 2023 / Professor Paul Knoepfler, Ph.D. / 2 Comments

I usually associate NPR with solid journalism so I was scratching my head about a recent puff piece by WHYY on stem cell microneedling. Is this journalism or product promotion? The NPR piece by Maiken Scott doesn’t ask important questions. Scott received stem cell microneedling herself using a product from a company called AnteAGE. How

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Weekly reads: human CRISPR, MRT risks, private IRBs, skincare

March 5, 2023 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

It’s funny how sometimes there are many new articles about one general topic like this week with heritable (and somatic) human CRISPR gene editing and related tech. There are clear reasons for optimism in the somatic arena given advancing trials. Germline editing remains highly questionable in my view even just technically. Then there are loads

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