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Gov Perry distances himself from Celltex, clinic that gave him stem cell transplant

June 26, 2012 / Professor Paul Knoepfler, Ph.D.

The big news yesterday was that the FDA report on its audit of Celltex went public and the report was a laundry list of FDA concerns. However, another very surprising and significant element of the story went largely unnoticed. I’m talking about Governor Rick Perry’s reaction to the story. Rick Perry was asked to comment […]

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Predictions heat up on FDA audit of Celltex

June 25, 2012 / Professor Paul Knoepfler, Ph.D.

Celltex is an adult stem cell company in the great state of Texas that reportedly has produced adult stem cell products used for the treatment of more than 100 patients with stem cells. We don’t know much about Celltex (e.g. it has no website), but I was hoping to change that in part via a

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The interactome of the adult stem cell universe

June 23, 2012 / Professor Paul Knoepfler, Ph.D. / 2 Comments

Adult stem cell clinics are growing fast across the U.S. and the world. Many questions surround them. How do they get patients? How does the money flow? How does the FDA view them? How do all the different parties interact?In science when we study how various proteins or other molecules interact as a system we

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The stem cell gestalt of Geron Goodbye and the future of ACT

June 22, 2012 / Professor Paul Knoepfler, Ph.D. / 6 Comments

Last year one of the biggest events in the stem cell field was biotech Geron punting its embryonic stem cell (ESC) program. Much consternation followed. Some folks opposed to ESCs happily pronounced ESC research dead. Some folks in favor of ESC thought the world was ending a year early. Others tried to look on the

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ICMS posts 483 report of FDA audit: still awaiting news on Celltex

June 21, 2012 / Professor Paul Knoepfler, Ph.D. / 5 Comments

The International Cellular Medicine Society (ICMS) is viewed somewhat skeptically by the stem cell community, but they are undeniably an important player in the stem cell world. A few weeks ago I interviewed ICMS President, Dr. Ricardo Rodriguez (see interview here), and then I provided recommendations here to the ICMS to improve their organization including a less adversarial

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How iPS cells germinated in part in Seattle in the 1980s

June 16, 2012 / Professor Paul Knoepfler, Ph.D. / 2 Comments

What if I told you I believe that iPS cells really began in Seattle in the 1980s? Call me crazy? Read on. We hear a lot about how iPS cells were first created in 2006 in Japan by Shinya Yamanaka. I often say this myself. However, as is the case with so much in science,

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TGIF: The good, bad and zombie stem cell headlines for week of June 15

June 15, 2012 / Professor Paul Knoepfler, Ph.D. / 3 Comments

It’s been another wacky week in the stem cell world ranging from the Zombie to the Magical. Well, at least it’s Friday, right? In the stem cell world a Friday is not that different than any other day as stem cells often require 7-days a week care, but still Fridays are nice. OK, the

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Meeting with Rick Perry to build stem cell bridges

June 13, 2012 / Professor Paul Knoepfler, Ph.D. / 23 Comments

On Monday I had the privilege to participate in a very unique meeting down in San Diego, CA with Governor Rick Perry of Texas. The focus was on the future of stem cell translational research and clinical application. The small meeting was hosted by Jerry Henberger of the Parkinson’s Association of San Diego, at the Scripps

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What are the best iPS cell papers so far?

June 11, 2012 / Professor Paul Knoepfler, Ph.D. / 5 Comments

What are the most important iPS cell papers so far? 1) Yamanaka’s first paper on mouse iPS cells. Revolutionary. Intriguing perspectives presented in day 1 of the iPS cell field. Interesting statements such as Myc is required. Also take a look at those other reprogramming factors that he tested…there’s a tremendous amount there, largely unexamined.

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FDA visits both ICMS and reportedly Celltex

June 6, 2012 / Professor Paul Knoepfler, Ph.D. / 6 Comments

The FDA has been busy with stem cell-related activities this spring including with ICMS. Busier than publicly apparent. Very busy, indeed! Earlier, I reported that they issued a warning letter to cosmetician to the stars, Dr. LookGood, as well as one to another doc selling stem cell therapies. Now it seems apparent that even more

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