This is a crowdsource page for people who want to post their findings on their attempts to validate the STAP stem cell ( ＳＴＡＰ細胞) method. I’m going to color successful or even moderately encouraging reports green and failures/discouraging results in red. *For those with longer attention spans, see some additional important considerations for this crowdsourcing effort at […]
I spend some hours each week reading and thinking about the recent scientific literature and I’m sure many of you do the same thing, but do we gravitate towards hyped “holy crap” papers? Every so often, a new paper erupts on the scene. It makes a big splash with a flashy entrance that captures people’s
The ‘Holy Crap’ Effect: Reflecting on Big Splash Papers Read More »
Congratulations to my new friends Paolo Bianco, M.D., of Sapienza University of Rome (pictured at left), Elena Cattaneo, Ph.D., of University of Milan and Michele De Luca, M.D. of University of Modena and Reggio Emilia (photo in the middle of the post), for receiving the 2014 ISSCR Public Service Award. Drs. Bianco, Cattaneo, and De Luca are
Congrats to Bianco, Cattaneo, & De Luca for ISSCR Award Read More »
I recently posted on the dangerous situation with the Stamina Foundation. I discussed the controversy surrounding it that has impacted scientists, politicians, the media, and patients. Stamina’s unproven stem cell treatments in Italy should be of concern to everyone across the globe in the stem cell field. For example, here in the US where I
More on Stamina Foundation Controversy: Letter from Michele Simonato Read More »
2014 Epigenetic mechanisms of tumorigenicity manifesting in stem cells. Tung PY, Knoepfler PS. Oncogene. Jun 16;0. doi: 10.1038/onc.2014.172. [Epub ahead of print] Histone H3.3 regulates dynamic chromatin states during spermatogenesis. Yuen BT, Bush KM, Barrilleaux BL, Cotterman R, Knoepfler PS. Development. 2014 Aug 19. pii: dev.106450. [Epub ahead of print] Miz-1 Activates Gene Expression via a Novel Consensus DNA Binding Motif..
Knoepfler Lab Publications Read More »
CIRM, the California Stem Cell Agency, is looking for a new President since current President Alan Trounson announced that he will be moving on at some point in the near future. CIRM itself is undergoing changes as it anticipates a key turning point in 2017 when it will not have state funding from Prop 71
More on CIRM’s Search for a New President Read More »
By Jeanne Loring “Shared Labs Axed” was the headline for David Jensen’s blog about the California Institute for Regenerative Medicine, the funding agency founded after voters approved Proposition 71, the “stem cell research and cures” initiative. I was there when the ax fell, in Los Angeles at the meeting of CIRM’s governing board, along with
Guest Post By Jeanne Loring: Efforts to Save CIRM Shared Labs Read More »
The Knoepfler Lab conducts stem and cancer cell as well as chromatin/epigenetics research at the UC Davis School of Medicine. Our team has two big picture goals: (1) catalyzing the development of more effective treatments for cancers based on targeting stem cell-related machinery in tumorigenesis and (2) producing safer stem cell-based regenerative medicine therapies. We are particularly
Scientific reviews and scores are in for CIRM’s Disease Team III RFA. We don’t know the identifies of the applicants yet, but 3 out of 4 of the top scoring grants recommended outright for funding are focused on cancer. As a cancer stem cell researcher (and cancer survivor) I’m excited to see how well these
Cancer Grants Perform Well With CIRM Disease Team Reviews Read More »
A big, fat elephant in “the room” of the commercial stem cell field today is something called stromal vascular fraction or SVF, made from human fat tissue or adipose. If you care at all about stem cells or the stem cell field more generally, you had better educate yourself on SVF. You can learn a
Law and Order SVF: what is stromal vascular fraction? Read More »