October 29, 2020

The Niche

Knoepfler lab stem cell blog

Most people believe in limited stem cell homing

Stem Cell Homing Poll
Stem cell homing poll results.

I recently did a poll on stem cell homing.

As you can see from the poll results above, most respondents believe that stem cells can home depending on circumstances. Almost 2/3 of respondents believe that stem cells sometimes or always home in to areas of disease.

However, most respondents did not believe in this being a universal property.

Why would stem cells home to diseases? It seems that injured tissues release cytokines that attract certain cells including immune cells. Maybe stem cells too?

It’s also possible that injured tissues change the adhesion molecules they express on their surfaces so that stem cells tend to stick and then stick around.

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