The other day I was talking with some folks about stem cell policy on Zoom, which was great, but one phrase from them jumped out at me and gave me a laugh. “Joe Rogan is the Gwyneth Paltrow for bros.” It also just rings true to me.
Some readers of The Niche may remember that I’ve written before about a particularly awful Joe Rogan stem cell video that promotes unproven clinic offerings. See image above. However, he has promoted unproven stem cells numerous times and apparently has gotten injections of stem cells too himself.
In that sense, like Gwyneth Paltrow, he’s promoting unproven health-related offerings. I wonder who would be more offended by the comparison? I’ll write more about all the Joe Rogan videos mentioning stem cells sometime later.
Okay, on to the recommended reads for the week.
Stem cell pubs
- The exploration of pluripotency space: Charting cell state transitions in peri-implantation development, Cell Stem Cell.
- The American stem cell sell in 2021: U.S. businesses selling unlicensed and unproven stem cell interventions, Cell Stem Cell. Leigh Turner follows up on his and my previous 2016 paper collecting data on clinics. The new data are mind boggling. The unproven stem cell clinic industry is like a cancer growing quickly. Can the FDA do something meaningful at this point? I think so and I’ll write more about that this coming next week.
- Nonbone Marrow CD34+ Cells Are Crucial for Endothelial Repair of Injured Artery, Circulation Research. I got my start in science by growing human umbilical cord vein endothelial cells. Way back then I had a crash course in endothelial cell biology. These little guys form cobblestone-like sheets in every blood vessel and are important for normal vessel function. It’s interesting to see that blood stem cells are involved in their repair.
- Synonymous mutations reveal genome-wide levels of positive selection in healthy tissues, Nat Gen. The idea of clonal expansion of cells in the blood and even in the skin has received a lot of attention. It makes good sense that such expansion could be a prelude to cancer if driven by slightly faster growing cells.