Weekly stem cell reads: parabiosis, UC Davis trial, HeLa lawsuit, gray hair

Parabiosis refers to the joining together of two animals, typically rodents in research. They become one interconnected living system that shares blood. Research on mouse parabiosis has sparked much interest in anti-aging therapies. These might utilize “young” materials to help older people. Our first recommended read is a parabiosis paper.

Parabiosis, anti-aging
Schematic of Parabiosis in mice where their joining leads to exchange and sharing of biological materials like blood.

Before we jump into that, it’s great to note several milestones recently here for the stem cell blog. Our The Niche educational outreach program providing info on stem cells in 34 languages crossed the 2.5 million reads milestone.

Also, our stem cell YouTube channel crossed the 30,000 views mark. With about 480 subscribers we are nearing the 500 subscribers milestone. Please subscribe and help us get over the 500 mark. You can see a fun video from the channel below.

Parabiosis paper

Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues, Cell Stem Cell. We’re back to the young blood anti-aging world again with this new paper. Past research has shown when the two mice are sewn together consist of one young and one old mouse, that they impact each other. The older mouse begins to exhibit signs of a younger phenotype, and vice versa. This new parabiosis paper also brought to mind the recent young CSF paper. It claimed that young CSF when infused into the cranial cavities of older mice led to more youthful brains in the old mice. In the new paper they report that parabiosis causes a more youthful profile of many tissues including blood, bone, liver, and nervous system. It’s a comprehensive paper.

Other stem cell weekly recommended reads

3 thoughts on “Weekly stem cell reads: parabiosis, UC Davis trial, HeLa lawsuit, gray hair”

  1. Maybe because some people don’t want to look 10-20 years older than they are.

    The real question is why you feel the need to gaslight people on this topic…

  2. Regarding parabiosis, how are the rats selected for “sewing together”. Don’t they have to be extremely well-matched genetically? What percentage of these experiments end with dead rats due to graft vs host issues?

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