September 24, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: cloning

3 min read

My weekly roundups of biomedical news tend to focus on stem cells, but I read more broadly so it’s not just stem cells but also CAR-T cells and a lot more this week. CAR-T cells as senolytics? A team led by Scott Lowe has a new intriguing paper in Nature on using CAR-T cells to target senescent cells. The paper is entitled, “Senolytic CAR T cells reverse senescence-associated pathologies”. The core idea here is that CAR-T cells can be used to get rid of …Read More

3 min read

“If I’m going to the trouble of cloning myself, I want the clone to be a copy of me!” I’m imagining what someone might say if they were told that their expensive and ethically dubious personal cloning efforts produced a clone that was somebody else instead of them. Even if the clone was very similar to the clonee, perhaps like a sibling who was nearly but not quite an identical twin, the clonee might be totally PO’d. When I think about “human “cloning” I …Read More

4 min read

Is monkey cloning a good idea? We’re about to find out. A new Cell paper today reports the first cloning of monkeys via somatic cell nuclear transfer (SCNT), raising many questions. The paper from a team led by Qiang Sun is entitled, “Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer.” The highlight bullet points from the paper are the following: “•Somatic cell nuclear transfer (SCNT) using fetal fibroblasts yielded two live monkeys •Epigenetic modulators promoted development and pregnancy rate of SCNT embryos •SCNT …Read More

1 min read

Sounds recommended weekend reads for you to enjoy since it is Friday and almost the weekend including stem cells, CRISPR, cats, cloning, and more. Holy GMO, China wants to buy Syngenta. RetractionWatch says that Macchiarini will soon be out at Karolinska. For more on this “super surgeon” who used stem cells, see here regarding recent Vanity Fair Expose. David Jensen on CIRM and human genetic modification: no germline work funded now, but possible in the future. This is pretty awesome. Canadian ‘dream team’ to probe stem-cell …Read More