May 31, 2020

The Niche

Knoepfler lab stem cell blog

Search Results for: doudna

3 min read

A recent piece on CRISPR genetic modification in the New Yorker called The Gene Hackers or Human 2.0 by Michael Specter is striking in a number of ways. I highly recommend it. The article provides an in-depth look at CRISPR and its potential use for human editing. I like how the article brings so many viewpoints to bear on this important topic. The thing that struck me the most was the recounting of a dream, really a nightmare, that left CRISPR pioneer Jennifer Doudna …Read More

2 min read

The House Subcommittee on Research and Technology on Tuesday held a hearing: “The Science and Ethics of Genetically Engineered Human DNA”. At the meeting, CRISPR pioneer Dr. Jennifer Doudna gave testimony along with Dr. Victor Dzau who is the President of the Institute of Medicine (IOM) of the National Academy of Sciences (NAS), Dr. Elizabeth McNally who is Professor at Northwestern, and Dr. Jeffrey Kahn, a Professor and bioethicist at Johns Hopkins. A screenshot of Doudna testifying is shown above. Note that the NAS …Read More

1 min read

With more than 250 votes cast, Jennifer Doudna is leading by a decisive margin in a poll asking who deserves the patent for use of CRISPR-Cas9 as a tool. Feng Zhang got only just over half the votes of Doudna. Another take home message from this poll is that a sizable minority–almost one in five– said neither should have a patent on this technology. Geographically the results were fairly consistent across countries, but notably in the UK the top response was, “Neither”. This poll is …Read More

9 min read

I’m doing a series of interviews with leaders in the field on human germline modification with the first interview in this series with George Church and today’s second in this series is a conversation I had with Dr. Jennifer Doudna, a pioneer in CRISPR-Cas9 technology. Doudna is a Professor in MCB and Chemistry as well as Li Ka Shing Chancellor’s Chair in Biomedical and Health Sciences at UC Berkeley. She is also an HHMI Investigator. You can read more about the Doudna lab’s research here. …Read More

Over the years I’ve done a variety of videos that ended up on YouTube and while most of these were stem cell videos, some deal with other important topics such as CRISPR of human embryos. You can see an image from a PBS interview video at left that was particularly memorable (more below). In this post I include links to these videos and short summaries of what went into them. I’m planning to include many more new videos in the future. The above video …Read More