September 20, 2020

The Niche

Knoepfler lab stem cell blog

Neuro

4 min read

What’s new this week in terms of reads includes a stem cell/drug combo for diabetic wonderments healing, more documentation of patient harms from stem cell clinics, and a list of recommending papers. Adult stem cells/glaucoma drug combo promotes diabetic wound healing in mice From a team of my UC Davis School of Medicine colleagues led by Rivkah Isseroff, Jan Nolta, Athena Soulika, and Thomas Peavy we have in Stem Cells Translational Medicine this exciting new paper, Combination product of dermal matrix, human mesenchymal stem cells, …Read More

2 min read

At the recent RPI stem cell and bioengineering meeting, the Neural Stem Cell Institute’s Sally Temple talked about her group’s intriguing retinal pigmented epithelial cell (RPE) research. With the broad focus of attention in the world of RPEs mostly on those derived from either human ESC or IPSC, it was exciting to here about the adult RPEs that Temple’s group has isolated and characterized (e.g. see this paper). Although only about 3% of cells isolated from the human retina turn out to be retinal …Read More

3 min read

Why doesn’t the brain fix itself using stem cells the way other organs do? Earlier this week I was lecturing to students here at UC Davis on stem cells. One of the points I raised was that most if not all of our organs have a compliment of stem cells that are there to maintain the organ and fix it when sick or injured. I also pointed out that although there are stem cells in the brain, surprisingly there is little evidence that these …Read More