January 18, 2021

The Niche

Trusted stem cell blog & resources

stem cell news

2 min read

A few times a month I do a recommended reads kind of post on more than just stem cells, which people seem to appreciate as a condensed list of new science and medicine. Scientists might ask each other, “what’s in your to-read list?” rather than “what’s in your wallet?” Here are some of the things I’m hoping to get to in coming days or have already taken a look at that seem worth a read. If you want to see last week’s reads here …Read More

4 min read

What’s on your weekend reads list including stem cell papers? In addition to hard-core research papers, I find some bigger picture publications to be helpful too. Then there are just fun items. Every so often I do a post about things that I’m hoping to find time to read over the weekend or that I’ve recently read. Today’s post is one of those items and here are some interesting science reads related in particular to stem cells, cancer, and CRISPR. Stem cell research and …Read More

2 min read

Once or twice a month I do a post on notable stem cell publications and news, which often but not always include research on iPS cells. It’s sort of a recommended reads kind of post, but I often include one or two things that aren’t necessarily recommended exactly yet seem kind of surprising or novel in some ways. Here’s today’s list. One bit of news first On the RMAT front: “FDA Grants RMAT Designation for CAR T-Cell Therapy for Multiple Myeloma.”  You can see …Read More

2 min read

When it comes to coverage of stem cell research in the media, science news can both be cool, but also surprising. Some of the more interesting publications don’t always draw news coverage too. This post is a list of recent notable pubs and news. First some pubs. How good are human brain organoids at modeling human brain development? A new meeting abstract from the Arnold Kriegstein lab (covered here at The Scientist) claims not so good. The abstract concludes, ” Although organoids are a …Read More

2 min read

The exciting and sometimes downright crazy giant stem cell ecosystem of legit research and unproven stem cell clinics could use a dose of good news now and then. In today post, I highlight some upbeat news and some interesting recent pubs. Enjoy! From a team led by Hina Chaudhry, MD, Director of Cardiovascular Regenerative Medicine at the Icahn School of Medicine at Mt. Sinai, a new PNAS pub, “Multipotent fetal-derived Cdx2 cells from placenta regenerate the heart.” Congrats to first author Sangeetha Vadakke-MadathilThis is a …Read More

1 min read

What new papers and news in the stem cell sphere caught your eye? Here are some recent items that seem notable to me. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. This paper reports cellular reprogramming to insulin-producing cells in mice. They reprogrammed α-cells with Pdx1 and MafA proteins. ‘Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease’ in Nature Neuroscience. Using IPS cells for insights. “What open chromatin features predict pluripotency?” asked and answered by the authors of this review …Read More

3 min read

Stem cells are always in the news so what’s up in the last week or two? CIRM News The dialogue over CIRM’s future is picking up a bit of steam. The San Francisco Chronicle did an in-depth piece on CIRM some weeks back and then opined that they didn’t feel supportive of another round of funding. I disagree. I think CIRM is a good future investment for California, but as a past CIRM grantee and stem cell advocate my opinion is probably not a …Read More

2 min read

Sometimes we could all use a jolt of good news and cool science. Those of us in the stem cell field probably get tired at times of all the bad-ish, even if important news (like this from Michael Hiltzik of the LA Times) out there surrounding certain unproven stem cell offerings and also clinics that engage in all kinds of stuff ranging from off-beat shenanigans to really dark stuff. Today’s post is focused mostly on the good news and exciting science. You can see …Read More

2 min read

Stem cell news is always burbling up, sometimes right there in front of us on the web and other times via networks of people. Astellas news. Some may remember there used to be this pioneering stem cell biotech called ACT, which then became Ocata, and finally was acquired by the big company Astellas. One of their areas of focus was on using pluripotent stem cells for macular degeneration. The driving scientific force was (and is) Dr. Robert Lanza. About a year ago I had …Read More

2 min read

How does one keep up with all the regenerative medicine and stem cell happenings? There is always something happening in the stem cell and regenerative medicine field ranging from science to policy matters. This post is an update on some recent stem cell happenings that I see as notable or interesting. New Pubs Direct reprogramming pub. One of the more interesting recent papers was from direct reprogramming guru Marius Wernig as his team came out with a new transdifferentiation paper that strikingly reports conversion …Read More