Vision

Vision research and vision loss

Weekly reads: Stem cells for vision loss & recommended pubs

stem cells for vision loss ribeiro et al

I’m going to start off today’s recommended reads post with some stem cells for vision developments. I had some fun the last 2 weeks as people sent in their entries for our $100 stem cell picture contest. I’ll announce the winner this week. It’s going to be hard to choose given the great entries. Stem …

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Recommended stem cell reads: retractions, aging, COVID, CRISPR soldiers

lu et al nature eye regeneration

This week we have some interesting new reading including both on the stem cell basic and translational fronts as well as on COVID-19 vaccines. COVID-19 vaccine considerations From Derek Lowe at In The Pipeline on COVID-19 vaccine expectations at Science Translational Medicine, Get Ready for False Side Effects. You can read my views on possible …

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Recommended regenerative medicine reads: COVID-19 updates, Cornea Fix, Pubs

2019nCoV-NP-cardio-myocytes

Another week and more great papers and interesting news in the regenerative medicine sphere including COVID-19 updates, stem cells for vision, and more. Rebuilding Corneas With Stem Cells Stem cell-based regenerative medicine arguably has shown the most promise for vision loss. A PR from Massachusetts Eye and Ear says: Doctors rebuild damaged corneas using patients’ …

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Groundbreaking Organoid Vision Clinical Study: Takahashi Q&A

Mandai-et-al-Stem-Cell-Reports-2017

Clinical trials using organoids are still rare and a Clinicaltrials.gov search for such organoid work largely brings up in vitro studies. A new clinical study in Japan where organoid material will actually be transplanted into patients is causing a lot of excitement. Masayo Takahashi (高橋 政代) is a pioneer in stem cell-based clinical trial work …

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1st autologous IPS cell clinical trial for vision loss in the US

Fig.-4a-Schaub-et-al-JCI-2019-

The NIH announced the launch of the 1st autologous induced pluripotent stem (IPS) cell trial for vision loss in the U.S., focused on macular degeneration. The protocol is based on a solid foundation of pre-clinical animal studies: “Researchers at the National Eye Institute (NEI) are launching a clinical trial to test the safety of a …

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Recent stem cell news: vision, brain organoids, & lab meat

human-corneal-anatomy2

365 days a year, 24 hours a day stem cells are growing in labs around the world, providing a never-ending stream of data and products, with real hope, good news, and lots of surprises. You can see some past examples of good news in the stem cell and regenerative medicine field highlighted on The Niche here. …

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Possible safety concerns from new stem cell, RPE vision loss study report

Figure-1-Mehat-et-al.-AAO-Journal-2018-810x1024-1

With stem cells for vision loss, first we want to be sure a treatment won’t make things worse. Several teams around the globe are rigorously studying stem cell-based approaches to vision loss via regulatory-compliant studies including for macular degeneration with some results cautiously upbeat on safety from early phase analyses, but data from a new study on …

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15 still unanswered interview questions for stem cells for vision SCOTS trial docs

George-Gibson-SCOTS-patient-screenshot-of-Sun-Sentinel-video-1

There’s a lot going on in Florida with non-FDA approved stem cell offerings even just related to stem cells for vision problems alone, but while US Stem Cell has drawn the most attention related to patient allegations of severe vision loss in Florida after fat stem cell injections in eyes, another group I’ll loosely call the …

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New lawsuit includes big stem cell clinic chain, Cell Surgical Network

Walraven-Cell-Surgical-Network

Does a new lawsuit including Cell Surgical Network and its leadership as defendants pose a broad test to this entire chain of stem cell clinics, which may be the largest such affiliated clinic group in the U.S. and potentially even in the world? Will lawsuits substantially impact stem cell clinics? Lawsuits against unproven, for-profit stem cell …

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