You searched for reprogramming - Page 2 of 25

Recommend reads: CRISPR baby guy free, DNMT3, sperm, Editas, hearing loss, reprogramming

April 17, 2022 / Professor Paul Knoepfler, Ph.D. / 3 Comments

We often don’t think of them that way but reproductive cells like sperm and egg are also relatives of stem cells, and it turns out that there are stem cells that make the reproductive cells too like sperm stem cells. Sperm and germ cell stem cells DNMT3A-dependent DNA methylation is required for spermatogonial stem cells […]

Recommend reads: CRISPR baby guy free, DNMT3, sperm, Editas, hearing loss, reprogramming Read More »

Weekly reads: lab meat, crow brain biology, direct reprogramming, more

September 27, 2020 / Professor Paul Knoepfler, Ph.D. / Leave a Comment

Does time seem somewhat warped to anyone else in 2020 even without having had COVID, which could alter brain function? It just seems like with everything going on that time simultaneously both drags and zooms by this year. One sort of reassuring element is that papers keep on being published so we can enjoy cool

Weekly reads: lab meat, crow brain biology, direct reprogramming, more Read More »

Recent stem cell pubs & news: reprogramming, chromatin, single-cell, Astellas, & more

February 18, 2019 / Professor Paul Knoepfler, Ph.D.

What new papers and news in the stem cell sphere caught your eye? Here are some recent items that seem notable to me. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. This paper reports cellular reprogramming to insulin-producing cells in mice. They reprogrammed α-cells with Pdx1 and MafA proteins. ‘Mitophagy inhibits amyloid-β and tau pathology and reverses

Recent stem cell pubs & news: reprogramming, chromatin, single-cell, Astellas, & more Read More »

Cool stem cell papers: antibody reprogramming, organoids, gravity, & more

September 13, 2017 / Professor Paul Knoepfler, Ph.D.

The past few weeks have brought some exciting, thought-provoking stem cell papers and developments in the regenerative medicine field. Here’s a list of stem cell papers in the media that struck me as particularly cool along with some other developments in the field. Human Stem Cells Fight Parkinson’s Disease in Monkeys Organoids Reveal Clues to Gut-Brain

Cool stem cell papers: antibody reprogramming, organoids, gravity, & more Read More »

Shinya Yamanaka at ISSCR 2016 on reprogramming of cells & scientists

June 23, 2016 / Professor Paul Knoepfler, Ph.D.

The second day of ISSCR 2016 started off with a great session on pluripotency and plasticity, and the first talk was by Shinya Yamanaka. He changed the title of his talk to “Reprogramming of Cells and Scientist”. As with my other posts on this meeting, this one is a stream of quotes and impressions from

Shinya Yamanaka at ISSCR 2016 on reprogramming of cells & scientists Read More »

Big stem cell news: dynamic duo of all-chemical direct reprogramming reports

April 28, 2016 / Professor Paul Knoepfler, Ph.D. / 8 Comments

What is direct reprogramming ? There’s some big, positive news on this stem cell front today. All chemical direct reprogramming Two new innovative papers both by teams led by Sheng Ding of Gladstone Institutes with UCSF report all-chemical direct reprogramming of human somatic cells. Ding’s team took skin cells and by exposing them to cocktails of

Big stem cell news: dynamic duo of all-chemical direct reprogramming reports Read More »

Fuzzy New Stem Cells Bring Cellular Reprogramming into Focus

December 10, 2014 / Professor Paul Knoepfler, Ph.D. / 2 Comments

How cool is it that literally fuzzy new stem cells called “F-class cells” bring substantial new sharp focus to the cellular reprograming arena? Remember Project Grandiose led by the great stem cell scientist Andras Nagy? It’s a massive project intended to decipher what makes stem cells tick and how ordinary cells be changed or reprogrammed into powerful

Fuzzy New Stem Cells Bring Cellular Reprogramming into Focus Read More »

Sherley patent for reprogramming method like STAP cells

June 26, 2014 / Professor Paul Knoepfler, Ph.D. / 7 Comments

A new patent has been awarded to James Sherley for a very unusual method claimed for making induced pluripotent stem (iPS) cells. The patent, No. 8,759,098, claims that a single non-genetic chemical agent, xanthine, can by itself reprogram adult stem cells (ASC) into iPS cells (aka iPSCs; see image they released at left). Surprising patent, huh? Another

Sherley patent for reprogramming method like STAP cells Read More »

Cool Cell Stem Cell Paper From Ishii Team on Histones & Reprogramming

March 6, 2014 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Two of my favorite things are stem cells and histones. When they both come together in one paper and it’s in my favorite journal, Cell Stem Cell, you’ve got my full attention. My own lab is especially interested in the roles of histones and Myc in stem cells. So when I saw a paper a paper from

Cool Cell Stem Cell Paper From Ishii Team on Histones & Reprogramming Read More »

Search Results for: reprogramming