The annual ISSCR meeting has started in Stockholm. This is always a great annual meeting both for the science and for connecting with people including new friends and colleagues as well as old friends. Another element to the meeting is the insider conversations in the halls, restaurants, and bars that tell a behind the scenes […]
Insider Trends on Stem Cells to Look Out for at ISSCR 2015 Stockholm Read More »
The challenge to the WARF/Jamie Thomson patents/IP on human embryonic stem cells (hESC) is at an end. The US Supreme Court declined to hear the case. Earlier, the USPTO had turned down the challenge leading to a winding road in the courts. What do you all think of this stem cell IP challenge and the
Supreme Court Rejection of WARF hESC Patent Challenge Discussion Read More »
Remember that old TV show the Odd Couple with very proper Felix Unger and his polar opposite Oscar Madison who has all kinds of baggage? They’ve cloned it into a remake to be on TV soon here in the US in 2015. It seems only fitting then that actual human cloning research has a new
The Odd Couple of Cloning Research: Mitalipov & Woo Suk Hwang Unite Read More »
2015 Review of Vogelstein “Bad Luck” Cancer & Stem Cell Paper in Science January 02, 2015 2014 What Does New Paper Mean for Future of Nuclear Transfer ES Cells? November 9, 2014 Encouraging New Paper on ACT Stem Cell-Based Trial for Macular Degeneration October 14, 2014 Top 10 Takeaways From Harvard Stem Cell Diabetes
Post-Publication Paper Reviews & Commentaries Read More »
A lot has happened in 2014 in the stem cell and regenerative medicine field and so much of it has been good news so let’s focus on the positive. These positive developments are often the result of many years of creative, hard work by amazing teams of researchers. Here is my top 10 list of
Positive Stem Cell Developments in 2014 Read More »
Advances in therapeutic cloning reported in the past year have been very exciting as somatic cell nuclear transfer (SCNT) can be used to produce very powerful human embryonic stem cells (ESC). These new cells are called NT-ESCs for short. Neither embryos nor reprogramming factors are needed to produce human NT-ESCs. See here, here and here for discussions of the pioneering papers reporting creation of
Future of Somatic Cell Nuclear Transfer to make ES Cells Read More »
Just how good are human embryonic stem (ES) cells made by therapeutic cloning via nuclear transfer, with the successful technique first reported by the lab of Shoukhrat Mitalipov at OHSU last year? How do they compare to induced pluripotent stem (iPS) cells or traditional ES cells made from IVF embryos? A new paper in Nature directly tackles these
Review of Mitalipov Nature paper: cloned ES cells vs iPS cells Read More »
What’s the biggest stem cell story of the year so far? I did a poll asking just that and the result so far overwhelmingly indicate that respondents believe the STAP cell scandal to be the top stem cell story of 2014 about half way through the year. You can see the results from the 210+
Poll indicates that STAP cells are stem cell story of the year so far Read More »
Two of my favorite things are stem cells and histones. When they both come together in one paper and it’s in my favorite journal, Cell Stem Cell, you’ve got my full attention. My own lab is especially interested in the roles of histones and Myc in stem cells. So when I saw a paper a paper from
Cool Cell Stem Cell Paper From Ishii Team on Histones & Reprogramming Read More »
What’s the latest surprise on the STAP cell front? There have been many unexpected turn along the way in the past few weeks of the rollercoaster ride the stem cell field is on related to STAP stem cells, the super powerful stem cells reportedly (in two papers in Nature) made “simply” by exposing cells to
Nature Post-Pub Examination of Its Own STAP Cell Papers Breaks New Ground Read More »