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Stem cell story of the year: human therapeutic cloning

December 18, 2013 / Professor Paul Knoepfler, Ph.D. / 8 Comments

There have been many interesting developments in stem cells in 2013, but to me the biggest event by far was the first ever successful somatic cell nuclear transfer (SCNT)-based human therapeutic cloning. This approach generated apparently genetically normal human embryonic stem cells (hESC), an astonishing accomplishment. There are two kinds of human cloning: therapeutic and reproductive. […]

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Key Questions for the Stem Cell Field for 2014

December 11, 2013 / Professor Paul Knoepfler, Ph.D. / 4 Comments

The World Stem Cell Summit in San Diego was a great meeting this past week. It was my 3rd straight Summit and the best of all. It’s a unique mix of science, medicine, and policy that links together key players from every corner of the field. I talked stem cells one-on-one or in small groups

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Hannah near-perfect reprogramming voted as iPS cell paper of 2013

December 5, 2013 / Professor Paul Knoepfler, Ph.D.

I recently did a poll asking readers of my blog to vote on the iPS cell paper of the year for 2013. The vote kind of seesawed at the beginning, but in the end with 100 votes cast the paper by the Hannah lab on near-perfect iPS cell production won out (see votes at left).

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Dozen Finalists for Stem Cell Person of the Year 2013

October 17, 2013 / Professor Paul Knoepfler, Ph.D. / 14 Comments

The voting is over and we have our top 12 finalists for the 2013 Stem Cell Person of the Year Award. You can see the final votes results below. It’s definitely an intriguing list that reflects the range of important areas in the field today. I can say without any hesitation that all 12 of

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Why Shoukhrat Mitalipov opposes human cloning

June 4, 2013 / Professor Paul Knoepfler, Ph.D. / 4 Comments

People have been confused about human cloning issues in the last few weeks on a number of levels. The confusion has come along with the excitement, concern, and increased interest in cloning lately since the lab of Dr. Shoukhrat Mitalipov reported a few weeks back in Cell the astonishing feat of successful human embryonic stem

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Interview with CAMR President & PAN CEO, Amy Comstock Rick

May 22, 2013 / Professor Paul Knoepfler, Ph.D.

As many of you know, the Coalition for the Advancement of Medical Research (CAMR) announced today that it will dissolve as an organization. I both emailed and talked on the phone with the President of CAMR, Amy Rick (who by the way is also CEO of the Parkinson’s Action Network (PAN)). Below is a concise

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Interview with Gil Van Bokkelen of Athersys

May 20, 2013 / Professor Paul Knoepfler, Ph.D. / 1 Comment

Today’s post is an interview I did with Dr. Van Bokkelen covering 10 questions. Dr. Gil Van Bokkelen is Chairman and CEO of Athersys, Inc., a company that has focused heavily on stem cells and regenerative medicine for more than a decade. For more on Dr. Van Bokkelen’s background see additional bio section at the end of

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5 human therapeutic cloning talking points dissected

May 16, 2013 / Professor Paul Knoepfler, Ph.D. / 9 Comments

Yesterday’s report of human therapeutic cloning to make embryonic stem (ES) cell lines is a big deal. I support the work and I believe it is very important. People’s reactions to it vary wildly depending on their agendas of course. This post is a no-nonsense overview of the main points. My overall point. This is

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Human cloning successfully makes embryonic stem cells

May 15, 2013 / Professor Paul Knoepfler, Ph.D. / 11 Comments

For the first time ever, scientists have successfully used somatic cell nuclear transfer (SCNT) via the process of therapeutic human cloning to generate normal human embryonic stem cells (hESC). Recall that there are two kinds of human cloning: therapeutic (which is reported in the new paper discussed in this post) and reproductive, which is making

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iPS cells top poll as most clinically promising pluripotent stem cells

May 14, 2013 / Professor Paul Knoepfler, Ph.D. / 3 Comments

I just closed my blog’s poll on what are the most clinically promising pluripotent stem cells. Why close the poll now less than 12 hours after I opened it instead of leaving the poll open longer? You’ll find out soon enough. I can’t resist teasing you readers sometimes. iPS cells were the big winners in

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