Search Results for: cancer stem cells

Recommended reads: regeneration by fasting & cancer, Time’s kid of the year, Hayflick death

Lizard growing new tail, regeneration

If only humans could master regeneration. It seems like that would open the door to far better health. Maybe to longer life too. We can see how many other creatures innately can regenerate organs. I can see it in the lizards that run around in my garden. Every now and then I see one with

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Recommended reads: MSC analysis points to challenges, IPSC NKs kill liver cancer, turning white fat into brown

MSC single cell transcriptome, MSC

Mesenchymal stromal/stem cells or MSCs are widely used by unproven clinics, but MSC research also suggests real promise in specific areas. Clinics mainly use adipose MSCs (often called SVF) or bone marrow MSCs. However, umbilical cord MSC preparations are getting more popular too. Many questions swirl around the use of MSCs including what exactly are

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Recommend reads: FDA SVF warning, big Aspen grant, CSI finale invokes stem cells

SVF

One of the most contentious areas in the regenerative medicine arena is whether a fat tissue product called stromal vascular fraction or SVF is a drug. The FDA says SVF, even in autologous form, is a drug. It is seeking an injunction against a California-based network of SVF clinics but lost the initial case. That

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Recommended reads: 3 infected in Mexico, stem cell hype, hearing restoration

muscle stem cell hype

Stem cell hype is a big problem these days. It’s been going on for decades. Even some generally good citizens of the stem cell and regenerative medicine arena engage in it at times. Maybe a few of them don’t even realize what they are doing. I think a few journalists occasionally fall into the hype

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Recommended reads: lung stem cells, Utah stem cell law, Ozzy gets cells

normal lung alveoli indicating examples at1 and at2 cells

We’ve known that most organs have resident stem cell populations for decades, but things have been less clear in the lung and it has only been relatively recently that lung stem cells have been definitively characterized. Why is so important? Lung stem cells, whether endogenous or made in the lab, have the potential to help

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Recent stem cell & regenerative medicine good news

stem cell good news, good news

Looking for some stem cell good news? You’ll like today’s post. One mission of this blog The Niche is to promote rigorous science-based regenerative medicine, which can lead to investigating and writing about not-so-upbeat stuff. Risky clinics. People getting hurt. Patient lawsuits. Serious FDA, FTC, or state AG regulatory developments. Such actions can be good

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Weekly reads: abundant Abcam prices, speedy aging & cancer, stemmy CAR-T, more on STAP

Abcam prices

When a vendor of important reagents like antibody supplier Abcam charges big money, those high Abcam prices could negatively impact research in the long run. Some of the prices are so high that buying just a few antibodies could take up a small but meaningful slice of an entire R01 grant. Sky-high Abcam prices I’ve

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Weekly reads: immune rejuvenation, Cryo-Cell spin-off, stem cell patches, direct reprogramming

Irv Weissman, immune rejuvenation

What is immune rejuvenation? How would that work and what would be the benefits? As we age, our immune systems can change in unhelpful and unhealthy ways. One such change is a drift in the balance of production of different kinds of immune cells. Such a shift can lead to too many of some immune

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Weekly reads: Alzheimer’s & lipid droplets, stem cells for COPD, fecal tx warning, med school teaching

Alzheimer's, lipid droplets Alzheimer's

So many things go wrong during the lead up to clinically-evident Alzheimer’s disease. This complex disease pathway has, in turn, led to a vast array of approaches to try to treat or prevent Alzheimer’s. Most of these efforts one way or another have something to do with the amyloid plaques and tangles that accumulate in the

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