TGIF: I’m working on an R01, but I still try to find time to read a wide variety of papers. Below are the science pubs that I’m hoping to get to this weekend. Less Myc, longer “health span” Cell paper from Sedivy Lab. ESC Histone H3.3 nucleosomal functions Epigenetics & Chromatin paper from Keji Zhao Lab. Human […]
TGIF: Biomedical weekend reading includes some cool papers Read More »
2015 Review of Vogelstein “Bad Luck” Cancer & Stem Cell Paper in Science January 02, 2015 2014 What Does New Paper Mean for Future of Nuclear Transfer ES Cells? November 9, 2014 Encouraging New Paper on ACT Stem Cell-Based Trial for Macular Degeneration October 14, 2014 Top 10 Takeaways From Harvard Stem Cell Diabetes
Post-Publication Paper Reviews & Commentaries Read More »
The Niche is the top, most authoritative stem cell and regenerative medicine blog on the web. It’s the only one to our knowledge written mostly by a professor. Professor Paul Knoepfler of UC Davis School of Medicine, an internationally respected stem cell biologist and educator, runs The Niche. Knoepfler is an advocate of rigorous evidence-based
About Us, The Niche and Knoepfler Lab Read More »
Many of this The Niche‘s readers ask about what my own lab’s research. What is the focus of the research of the Knoepfler Lab? You can go check out our lab website, but I thought it might be time to blog about what we are all about as a lab and what we have been
Knoepfler Lab: Our mission and research Read More »
It was great being a postdoc in Bob Eisenman’s Lab at the Hutch in Seattle with colleagues like fellow postdoc Shawn Cowley. I loved it. Bob is a great mentor (see more on my experience there here) and the scientific interactions in the lab were wonderful. It’s been fun and interesting to follow the work
Cool paper by Shawn Cowley Lab on the role of HDACs in ES cells Read More »
Happy St. Patrick’s Day and let me mention something else: St. Baldrick’s. How might you celebrate? At least in part you might consider supporting St. Baldrick’s, which is a wonderful foundation that supports research on children’s cancer. Every year they have a very cool event where supporters of the organization get their heads shaved to raise
How Baldness Helps Toward a Cure for Children’s Cancer: St. Baldrick’s Read More »
I believe that social media has on the whole had a strongly positive impact on the STAP cell situation that the stem cell field has been grappling with for 5 weeks. If the STAP method is proven to be correct at some later date, which is possible, it’s almost certain that those replication efforts will
Social Media Helps Field Deal With Stressful STAP Stem Cell Situation Read More »
Two of my favorite things are stem cells and histones. When they both come together in one paper and it’s in my favorite journal, Cell Stem Cell, you’ve got my full attention. My own lab is especially interested in the roles of histones and Myc in stem cells. So when I saw a paper a paper from
Cool Cell Stem Cell Paper From Ishii Team on Histones & Reprogramming Read More »
Vad är stamceller? means “What are stem cells?” in Swedish. This is part of our SCOPE stem cells not lost in translation project. Vad är stamceller? Den mänskliga kroppen innehåller hundratals olika celltyper, som alla spelar en viktig roll för vår hälsa. Cellerna gör så att våra kroppar fungerar som de ska genom att se
Vad är stamceller? Read More »
2014 Epigenetic mechanisms of tumorigenicity manifesting in stem cells. Tung PY, Knoepfler PS. Oncogene. Jun 16;0. doi: 10.1038/onc.2014.172. [Epub ahead of print] Histone H3.3 regulates dynamic chromatin states during spermatogenesis. Yuen BT, Bush KM, Barrilleaux BL, Cotterman R, Knoepfler PS. Development. 2014 Aug 19. pii: dev.106450. [Epub ahead of print] Miz-1 Activates Gene Expression via a Novel Consensus DNA Binding Motif..
Knoepfler Lab Publications Read More »