Search Results for: organoids

Weekly reads: CRISPR’d marsupial, outpatient recovery post stem cell transplants, Parkinson’s, pubs

CRISPR'd baby opossums.

This edition of The Niche weekly reads has a bit more good news than usual including on stem cell transplants. It’s nice to see positive developments like some recipients of hematopoietic stem cell transplants being able to stay at home afterwards. Also, a reminder. You have until July 31 to enter our stem cell video […]

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COVID Traps Alveoli Cells in a Curious Progenitor State, Squelching Lung Regeneration

normal lung alveoli indicating examples at1 and at2 cells

Mere weeks into the COVID pandemic, stunning graphics began to appear depicting the path of devastation of SARS-CoV-2 through a human lung. It’s only recently that we’ve come to understand what, exactly, is happening on a cellular level. The new view is thanks to single-cell RNA-sequencing, which analyzes the abundance of messenger RNAs in individual

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Weekly reads & stem cell news: New York axes NYSTEM, fetal tissue rules reversed, pubs & more

stem cell book

It’s been a week with a wide variety of regenerative medicine papers and stem cell news. Here’s my earlier take from a few days ago on the Belmonte-led human-monkey chimeric embryo paper in Cell that broke this week. A few days ago I also put up a new video on our Stem Cell YouTube Channel

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Fact check: Lung Health Institute & cell therapies for lung disease

the lung health institute

What should we make of clinics like the Lung Health Institute? These clinics sell unproven stem cell or regenerative therapies for lung disease. Overall, I’m extremely skeptical. I don’t believe it’s worth the cost. There are also going to be potentially serious health risks. Lung disease is a broad category including COPD, emphysema, pulmonary fibrosis,

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What are induced pluripotent stem cells or IPS cells?

induced pluripotent stem cells clinical trials map

Induced pluripotent stem cells or iPS cells just might be the most exciting development in the stem cell field over the last 15 years. They have unique potential for clinical impact for regenerative medicine too. This may manifest both through their use to produce differentiated cellular therapies and indirectly via disease modeling as well as

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What are totipotent stem cells & what can they do?

Multipotent & totipotent vs pluripotent stem cells, very early human embryos totipotent stem cells

Sometimes patients or my students ask me, “What are the best stem cells?” what information are they looking for? I think they often are looking for the most powerful stem cells so perhaps they should be asking, “What are totipotent stem cells?” Other times it seems what patients specifically want to know is what might

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