We’ve been hearing a lot this week about an important new clinical study for macular degeneration in the UK. This team is using retinal pigmented epithelial cells (RPEs) made from embryonic stem cells (ESC). They are now testing safety.
The new work in the UK is Moorfields Eye Hospital is a great addition to the growing list of stem cell clinical studies and provides real hope for those dealing with macular degeneration.
In their PR on the study, part of the London Project to Cure Blindness this is rightly described as a “major milestone” for the project. The co-leaders, Peter Coffey and surgeon Lyndon Da Cruz (pictured above), will guide this work.Pfizer is also part of the team for this study. I’m curious to see how it progresses and hopeful on the outcome.
There’s real reason for excitement in this area more broadly and that context is important to include, but many newspaper articles haven’t.
For instance, Ocata Therapeutics is doing very similar clinical work and is already years into its FDA-approved clinical trials for macular degeneration using RPEs made from ESC. So far that work has proceeded really well without safety concerns and with hints of efficacy. Also the clinical study in Japan for macular degeneration using IPS cells, while at present on hold, will likely start up again in a new iteration later this year or more likely in early 2016.
Disclosure: I have a very small, long-term position in Ocata stock.