Any day now we should get the verdict from the judge in the big stem cell clinic case here in California against Cell Surgical Network, et al. It seems that the FDA is waiting on this verdict before taking some major actions. If the judge rules against the agency it could throw the area into some at least temporary chaos.
With some papers in the works in my own lab I haven’t had as much time to read the literature. Here are some recommended reads that did catch my eye.
Stem cell and regenerative medicine news
ASH releases guidelines on stem cell transplantation for patients with sickle cell disease, Healio.
Biotech Cellino Raising $75 Million for Stem Cell Therapies, Business Insider.
- p53 inactivation unmasks histone methylation-independent WDR5 functions that drive self-renewal and differentiation of pluripotent stem cells, Stem Cell Reports
- Inner nuclear protein Matrin-3 coordinates cell differentiation by stabilizing chromatin architecture, Nat Comm.
- Type II collagen-positive embryonic progenitors are the major contributors to spine and intervertebral disc development and repair, Stem Cells Translational Medicine.
- Systematic review and meta-analysis of preclinical studies testing mesenchymal stromal cells for traumatic brain injury, npj Regenerative Medicine.
- Bone-forming perivascular cells: Cellular heterogeneity and use for tissue repair, Stem Cells. Review. The micro-anatomy or histology of the vascular wall is fascinating. There’s a lot more going on than you might think if you assume this is just the static wall for the “plumbing” of the vascular. See Figure 2 from this paper above.
- Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cellidentity, Cell Stem Cell.