I’ve been busy recently focusing more on grant and paper writing than reading papers on stem cells, but my piece on trying to de-extinct mammoths via cloning-like methods drew strong opinions on both sides.
Recent news and resources on stem cells
We’re still awaiting a verdict in the big California federal court case where the FDA is seeking a permanent injunction against the stem cell clinic chain Cell Surgical Network, et al. What will judge Bernal decide?
Don’t forget to check out The Niche Stem Cell YouTube Channel, where I have a variety of new videos on stem cells and other related topics. A recent one on head transplants is fun.
I also recommend checking out a cool FDA page where they list recent untitled letters. The number of FDA letters to stem cell clinics listed here is just a drop in the bucket compared to the apparently ~500 they’ve sent out recently but it’s still striking how many are on here. It does make me wonder how the FDA decides which of these letters to make public?
What science have you been reading recently? Here are some recommended papers with some emphasis on cancer mechanisms.
- Developmental chromatin programs determine oncogenic competence in melanoma, Science
- Transcriptional control of brain tumor stem cells by a carbohydrate binding protein, Cell Reports.
- Brick Strex: a robust device built of LEGO bricks for mechanical manipulation of cells, Sci Reports. See part of Figure 1b above.
- Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer, Nat Comm.
- Principles of signaling pathway modulation for enhancing human naive pluripotency induction, Cell Stem Cell.
- The Warburg effect is necessary to promote glycosylation in the blastema during zebrafish tail regeneration, npj Regenerative Medicine.
More on Myc
I included a section in our weekly reads post on publications related to Myc last week, but there are a few more notable papers this week. The first one is on the link between MYC and 3D chromatin structure, which I find particularly exciting.