Search Results for: crispr babies

Ukraine clinic plans to sell CRISPR enhancements: hair color, skin, & breast size

medeus clinic crispr enhancements

It was a couple of years back that researcher He Jiankui claimed he made three “CRISPR babies.” No one would think about doing any kind of rogue gene-editing again, right? Not even somatic gene edits. After all, as far as we know he’s in jail. We still don’t know the health risks that these three …

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Weekly reads: ‘junk DNA’, COVID chaos, CRISPR CasΦ, & postdoc opps, more

Retroviral-genes-Junk-DNA-NIHsmall

Here are our weekly recommended regenerative medicine and other notable science reads including a few things on COVID. It’s been quite an interesting week. “Junk DNA” is not so junky, role in differentiation NIH scientists showed how ancient retroviral genes, or “junk DNA”, may play a role in helping stem cells decide to become neurons. This …

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CRISPR often damages human embryo chromosomes

human-embryo-modification

Three new studies reported in preprints all show severe DNA damage to human embryos from CRISPR a surprisingly high percentage of the time including in some cases loss of heterozygosity (LOH). Anywhere from about a quarter to half of CRISPR’d embryos exhibited major genome damage. As readers of The Niche know, I never was a …

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Recommended recent stem cell, cancer, & CRISPR reads

Eyleen-de-Poel-and-Maarten-Geurts.-Image-from-UMC-Utrecht.

What’s on your weekend reads list including stem cell papers? In addition to hard-core research papers, I find some bigger picture publications to be helpful too. Then there are just fun items. Every so often I do a post about things that I’m hoping to find time to read over the weekend or that I’ve …

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Heads up on Hui Yang, another potential aspiring CRISPR baby researcher

-Yui-Hang

Making a CRISPR baby is a controversial idea to even propose now for many reasons, yet even after He Jiankui’s train wreck some people have seemed eager to try it including apparently a scientist whose name perhaps many readers here are not so familiar with in this context: Professor Hui Yang. ‘CRISPR baby guys’ Is …

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Perspectives on CRISPR baby guy He Jiankui (贺建奎) going to jail

Jiankui-He-who-claims-CRISPR-baby-production

Scientist He Jiankui(贺建奎) has been sentenced to 3 years in prison by Chinese authorities. Two collaborators also will go to jail. A piece in Science by Dennis Normile on the sentencing of He Jiankui ID’d the other two: “His collaborators were identified as Zhang Renli, of a medical institution in Guangdong province, and Qin Jinzhou, from a Shenzhen …

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CRISPR baby moratorium grows likely with rising tide of support including from biotech

CRISPR-gene-edit-vs-mutation-1

Trying to make a CRISPR baby any time soon would be a really bad idea. How bad? Last December 3rd I penned a piece for STAT News arguing for a moratorium on the heritable use of CRISPR in humans. This potential future, radical application of “gene editing” is now often colloquially referred to as “CRISPR …

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Weekend reads include herding brains, stem cells, & CRISPR

Stem-cells-the-niche-anti-aging

Every so often here on The Niche I list science and news articles worth a look as “weekend reads”. Below is my list for this weekend. Enjoy! The first article doesn’t really fit into the other main categories, but the title “herding brains” caught my eye. Stem Cells Stem cells and regenerative capacity in aging …

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Counterpoints to Lovell-Badge & Daley’s CRISPR baby rationales

CRISPR-baby

Two prominent scientists, Robin Lovell-Badge and George Daley, have been amongst the most outspoken proponents of leaving the door open to heritable human genetic modification via CRISPR. While they each have articulated their reasons in somewhat different ways at times, their core reasons arguing in favor of future heritable CRISPR appear largely the same. In …

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When the state & ‘rogue’ scientists collide: case of China & CRISPR baby guy He Jiankui (贺建奎)

He-Jiankui-贺建奎

What happens next to He Jiankui (贺建奎) or as some people now refer to him, the “CRISPR baby guy”? China has a challenging situation to resolve here, but such conflicts between scientists and governments have happened regularly in history. When scientists go “rogue” (i.e. don’t conform to norms or ethical standards in an extreme way or …

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