Search Results for: Gene Editing

Congress: FDA should consult religious experts on embryo CRISPR

Crystal_Structure_of_Cas9_in_Complex_with_Guide_RNA_and_Target_DNA

The US Congress recently held its first hearing on human germline genetic modification. The meeting included CRISPR-Cas9 pioneer Jennifer Doudna (see video here) on the panel. See image of Cas9 structure from Wikipedia. CRISPR-Cas9 is a powerful, strikingly efficient tool for genetic engineering of cells and whole organisms. Now Republican congressional leaders have included a …

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Recap of BEINGS 2015 Meeting by Aaron Levine: Shaping Future of Cellular Biotech

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Last week I attended Biotech & the Ethical Imagination (BEINGS 2015), the summit I previewed on this blog back in early May. It many ways the summit lived up to its lofty ambitions. Steven Pinker kicked off the event by emphasizing the power and importance of biomedical research, noting that almost everyone is affected by …

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White House supports moratorium on heritable human CRISPR

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The Obama Administration today weighed in on human germline genetic modification such as via CRISPR via a note from John Holdren, Assistant to the President for Science and Technology, and Director of the White House Office of Science and Technology Policy. The White House indicated support for the National Academy of Sciences (NAS) and the National Academy …

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DIY human ‘upgrades’ via biohacking

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Heritable human genetic modification has been the topic of the year so far, but another trend is edgy and interesting: non-heritable, but cutting edge forms of human modification that in some ways fall into the class of biohacking. Biohackers are into do-it-yourself (DIY) forms of biology including self-modification. Sure, people have been modifying themselves for …

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Hank Greely Human Germline Modification Post

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Hank Greely over at The Center for Law and Biosciences at Stanford Law School was one of the participants in the recent Napa meeting on approaches to human germline genetic modification. Hank was also one of the authors on the resulting position paper in Science with David Baltimore as first author (here). Now Hank, pictured below, …

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David Baltimore, et al. path for human germline engineering

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In a new perspectives piece in Science, Nobel Laureate David Baltimore and co-authors including Jennifer Doudna and George Church, chart a potential path forward for human germline engineering. See also accompanying Bioethics piece by Gretchen Vogel as well, “Embryo engineering alarm”. In the piece, entitled “A prudent path forward for genomic engineering and germline gene …

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Weekend Reads from a Wild, Fun Week of Science

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You might enjoy the recommended reads below and find they surprise and educate you. Products in the pipeline – Ocata’s RPE by Alexey, a nice update on Ocata. Yes, we are seeing more attacks on academic freedom: guest post by historian of science and medicine.  Guest piece by Alice Dreger on her new book, Galileo’s Middle Finger. …

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Big push for 3-parent IVF technology in UK

3-person-technology-letter

A new piece came out yesterday on the Wellcome Trust Blog, strongly promoting approval of so-called “3-Parent IVF” or Mitochondrial Transfer technology by the UK Parliament. As I written in the past (here and here), my view is that this would be a mistake at this time. There is room for respectful disagreement on this issue between scientists, …

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New Message from Wakayama on STAP retraction & origin of STAP-SC

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I have been corresponding now and then with Dr. Teru Wakayama about the ongoing STAP situation. He asked me to pass along the following message from him for clarification on the STAP Nature paper retraction and the origin of the STAP stem cells (STAP-SC). I would like to take this opportunity to explain the reason for …

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Interview with NIGMS Director, Jeremy Berg, part 1: grant advice, meritocracy

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Obtaining research grant funding is a critical part of science, but the process seems to be getting more challenging each year. Funding rates are decreasing. Applicant frustration is increasing and many grant applicants tell me they feel confused about the differences between funded and unfunded proposals. The largest funder of biomedical research in the U.S. …

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