If you’ve never heard of the KRAS G12C mutation, it’s a particularly frightening mutation present in numerous cancers. Like the MYC oncogene, many people view mutations in RAS as undruggable, but new efforts show some glimmers of hope. The drug Sotorasib has been approved by the FDA to target the KRAS G12C mutation. Here’s a […]
Weekly reads: KRAS G12C, eLife journal controversy, bird iPSCs Read More »
It’s always great to read about stem cell clinical trials that are looking encouraging. Stem cell clinical trials Proving a new therapy is safe and effective is so challenging. Remarkably, there are more than 9,300 stem cell clinical trials listed for a “stem cell” search on Clinicaltrials.gov. Of course, not all of these are actual
It was a shock to learn today that New York Stem Cell Foundation CEO and Co-Founder Susan Solomon had passed away yesterday after a long battle with ovarian cancer. I met Susan a few times over the years and was always struck by her positive energy. At a practical level she got big things done
Tributes to NYSCF leader & stem cell advocate Susan Solomon Read More »
The last six months I’ve been spending even more time than usual writing NIH grants (and a few others). The last two weeks have been especially busy on this front as I am getting an R01 renewal out the door. My paper reading lately has been mostly related to the grant writing I’m doing. Still,
Weekly reads: NIH grants, side effect of darker hair, FDA warning, CRISPR Read More »
Parabiosis refers to the joining together of two animals, typically rodents in research. They become one interconnected living system that shares blood. Research on mouse parabiosis has sparked much interest in anti-aging therapies. These might utilize “young” materials to help older people. Our first recommended read is a parabiosis paper. Before we jump into that,
Weekly stem cell reads: parabiosis, UC Davis trial, HeLa lawsuit, gray hair Read More »
Some people consider the brain to be equivalent to a living computer and in that sense it’s too bad that computers don’t have the equal of neural stem cells to help them fix themselves. Is the internet one big neural network-like web? There was a quake in the stem cell internet as CIRM’s main website
Weekly reads: neural stem cells, CRISPR brain, Vertex, cytoplasm surprise Read More »
Today’s post lists the best stem cell blogs and more generally the top biology blogs as well as websites. Making lists of “the best” of anything is fun yet it can be tricky. However, I feel that it can also serve a purpose as a resource. You might also enjoy these other “top” lists I’ve
22 best biology & stem cell blogs for 2022 Read More »
David Weinberg over at Science-Based Medicine has his part two of a deep dive into the so-called SCOTS trial, which is a non-traditional pay-for-play study. I highly recommend it. SCOTS trial under the magnifying glass In this piece, Weinberg provides interesting background on the two people running SCOTS. I’ve had many concerns about the SCOTS
Recommended reads: engineered niche, ALS, SCOTS trial, human genome “done” Read More »
When it comes to stem cells on Twitter and other social media, who do you follow now? Why them? Who are the top stem cell and regenerative medicine influencers to follow on Twitter and elsewhere in 2022? Stem cells on Twitter: great content amongst the noise Top stem cell and regenerative medicine influencers on Twitter.
50 influencers on stem cells on Twitter to follow in 2022 Read More »
I wrote briefly a few months ago about Altos Labs. It’s a new kind of biotech institute that is focused on cellular reprogramming. Now we know much more and it’s clear this is a huge deal. What’s in this article What is Altos Labs? | Cellular rejuvenation | Reprogramming oldness | Challenges | Altos Strategies | Analysis of
All about Altos Labs and $3B cellular rejuvenation push Read More »