I’ve been more interested in histones and their modifications versus DNA methylation when it comes to epigenetics and chromatin. In part this has just been because I have studied histones so much more. For example, we have been knocking out the two histone variant H3.3 genes, H3f3a and H3f3b, now for a decade. My lab also […]
Weekly reads: DNA methylation, H3 K27M in glioma, memory wipe, teeth Read More »
It’s great finding stem cell videos on YouTube that are either excellent research talks or provide important information. I recently found one such video by Shiri Gur-Cohen, which I included below. Interesting data there and Shiri is such a compelling speaker. She also won The Niche image contest one year with a cool microscopy pic
Weekly stem cell reads: Google Bard AI issues, fat ball reprogramming, BrainStorm on ALS Read More »
It wasn’t that long ago that Chinese scientist He Jiankui got out of jail. Why was he in there? For doing unauthorized human CRISPR to make heritably gene-edited humans. He botched that and apparently forged some approvals to make it happen. The three children involved may have life-long health problems as a result. I wrote
He Jiankui proposes editing human embryos again Read More »
So many things have gotten very expensive these days that it got me thinking this past week again about stem cell cost. For this reason, I’ve been running polls asking people what they’ve paid for stem cells and how many therapies they’ve gotten. Before jumping into our weekly reads, check out our informational post on
Weekly reads: stem cell cost, trial death, HSCT for MS, Neuralink Read More »
I’ve written before about Liz Parrish and her life-extension firm BioViva. Now they appear to have connections with another entity called Integrated Health Systems or IHS, according to a new Wired article. Some of what is going on with IHS and maybe BioViva in Mexico seems extremely risky to me. BioViva, Parrish, and Integrated Health Systems The
Weekly reads: BioViva & life-extension clinic, RMATs, universal cells Read More »
It’s mostly been a week of good and encouraging news in the regenerative medicine space including with gene therapies maybe with the exception of some eye drops warnings (more below). There’s realistic hope for an approved sickle cell disease soon. I also see some long-term positive news on hearing loss research. Hematopoietic stem cell transplant
Weekly reads: reprogramming hearing loss, heart disease, eye drops, sickle cell Read More »
Research on in vitro gametogenesis or IVG is jumping ahead and such work could one day lead to new infertility treatments. In vitro gametogenesis is the process of producing gametes (sperm and eggs) from stem cells. Those powerful stem cells, called iPS cells, can be made from ordinary adult cells like skin or blood cells.
Questions on National Academies in vitro gametogenesis (IVG) meeting sponsorship Read More »
Are there any guidelines for genomics studies of famous dead people like sequencing their genomes? It doesn’t seem like it. I remember when I first heard of the idea of trying to clone John Lennon from an old molar. Fortunately, as far as I know no one ever tried that, but it wouldn’t surprise me if
Pros & cons of dead celebrity genomics Read More »
Occasionally when I write a post there is an angry reaction to it in the blog comments, which was the case for my recent fact-check of the LifeWave X39 patches. As you can see in that post, I didn’t find convincing data to either back up the claimed stem cell connection. In my opinion, there
Weekly reads: bat stem cells & viruses, Lineage Cell, He Jiankui visa Read More »
I’m sure many of you remember He Jiankui, the guy who made CRISPR babies. He ended up serving three years in jail in China. He seems to be trying for something of a comeback since his release. Were He Jiankui invitations a mistake? Some prestigious places have even invited him to give talks, which seemed
Weekly reads: He Jiankui disappoints, ALS, Vor Biopharma Read More »