One of my main interests is the relationship between stem cells and cancer as well as what makes cancer stem cells tick. This week I’ve chosen to highlight articles on the role of stem cells in cancer plus other interesting publications. Cancer pubs related to stem cells including on cancer stem cells Identification of cancer-related […]
Weekly reads including MSCs & cancer stem cells Read More »
This edition of The Niche weekly reads has a bit more good news than usual including on stem cell transplants. It’s nice to see positive developments like some recipients of hematopoietic stem cell transplants being able to stay at home afterwards. Also, a reminder. You have until July 31 to enter our stem cell video
The paper of the week is from Science on making ovarian follicles and actual eggs from stem cells. It’s just in mice, but this line of work tends to stir people up. We’ll dive into that in a moment. But first some good news. We’re up to 146 subscribers on our stem cell YouTube channel
Weekly reads: stem cells to gametes, no PRP benefit, WHO CRISPR, pubs Read More »
The paper of the week is An isoform of Dicer protects mammalian stem cells against multiple RNA viruses published in Science. The take-home from the abstract is that the data, “demonstrate that mammalian stem cells can protect themselves from some RNA viruses by expressing an alternatively spliced isoform of the enzyme Dicer called aviD, which potentiates
Let’s start off today’s recommended reads with the topic of life extension. No controversy there, right? This comes to mind because of a new preprint from BioViva, Liz Parrish, and George Church. I’m hoping to cover this on our Stem Cell Channel on YouTube. Gene therapy and life extension research The preprint is entitled, “New
Weekly reads: life extension & BioViva, clinics & anti-vax, axolotls, systemic CRISPR Read More »
Cancer stem cells are one of the most interesting areas of research, intersecting the stem cell and cancer fields. Today’s weekly reads post highlights some new cancer stem cell articles along with some other interesting papers. I also note a recent weak stem cell clinical trial paper that is not a recommended read but is
Weekly reads: cancer stem cells & other pubs plus a puzzler Read More »
My to-read list this weekend includes a range of papers along with various news & media including a report of two US research groups aiming to get CRISPR baby patents. More on that below. At long last a trip + fun thing to do in NYC Last week I took my first trip in more
Weekly reads: escape to New York, CRISPR baby patents, ISSCR guidelines, pubs Read More »
Sometimes things in the stem cell world get complicated and this week is no exception with news of Orchard Therapeutics dropping a seemingly life-saving clinical trial. There are hundreds of kids who could possibly benefit. Rotten apple decision from Orchard Therapeutics From David Jensen at California Stem Cell Report we have something of a scoop:
Weekly reads: Orchard punts on life-saving SCID trial, cardioids with cavities, more Read More »
This was a busy week for me working on a grant due Friday and a bunch of other stuff including happily analyzing a bunch of data, but there were tons of interesting papers recently including on pluripotency. California stem cell clinic court case on in the background Along the way this week I was occasionally
Weekly reads: court case, cancer stem cells, skin, pluripotency, & more Read More »
One of my main research interests is in oncodevelopmental factors. These include factors that are important both for normal stem cell biology and development as well as driving cancer when misregulated. One example includes the MYC family of proto-oncogenes. When I was a postdoc I got especially interested in trying to understand the normal role
Weekly reads: oncodevelopmental factors, iPSC cancer vaccine, more Read More »