Search Results for: teeth

Lessons from sharks: how we might grow new teeth via stem cells

shark-new-teeth

What if we could grow new teeth from stem cells to replace lost ones or fix others that have big cavities again via tooth stem cells? While humans and some other animals like dogs have only two sets of teeth — so-called baby and adult teeth — in their lives, other animals aren’t so limited. For …

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Weekly recommended reads including asymmetric division & chromatin

Asymmetric division and chromatin

One of my favorite types of papers are those on stem cells and chromatin, and a new one in Current Biology caught my eye this week. My own lab website has the URL chromatin.com so that says something. You can also read more about our research here. Recommended reads: chromatin and stem cells, more Asymmetric …

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New data on stem cell clinics, INDs, & more including from FDA itself

arm slide fda trip program

The International Society for Cell & Gene Therapy or ISCT held a really interesting webinar yesterday on the FDA and unproven stem cell clinics. It was focused on the expiration of the FDA’s discretionary period on unproven stem cell clinics. What will the FDA do now? The webinar included some ideas and also quite a …

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Weekly The Niche Reads: tooth repair, PRC2, beach pics

brandts cormorant jumping sm

I managed to escape to do some hiking along the coast so I’m behind on my weekly reading and I’m just getting back here on The Niche. Here are some articles I’m hoping to catch up on in coming days including an interesting overview of stem cells for tooth repair. I sometimes have a wistful …

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What is a teratoma? Research & treatment

What is a teratoma? human stem cell teratoma knoepfler lab sm

Sometimes on The Niche or while teaching students as a professor here at UC Davis School of Medicine, I’ve been asked: What is a teratoma? Not all tumors are created equal and some like teratomas are particularly unusual. Exactly what is a teratoma? Teratomas are germ cell tumors. What this means is that the cells …

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Weekly reads: lab meat, crow brain biology, direct reprogramming, more

Stacho-et-al-Science-2020-Fig-1small

Does time seem somewhat warped to anyone else in 2020 even without having  had COVID, which could alter brain function? It just seems like with everything going on that time simultaneously both drags and zooms by this year. One sort of reassuring element is that papers keep on being published so we can enjoy cool …

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Mid-week rec reads: plague paleogenomics, bats, art, get new skin, & more

The-Dancers-III-IV-Marguerite-Humeau

I’m doing an experiment today to see if people enjoy a mid-week splash of a few Wednesday recommended science reads and the first one collides with art. You can see Sunday’s recommended weekly reads here too. Also, be sure to visit our Facebook page if you have a moment and please like our page if …

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Another FDA letter to a stem cell clinic supplier: what’s the agency’s long game?

FDA-untitled-letter

The FDA just sent another untitled letter to a producer of a potentially non-compliant perinatal “stem cell” product that may be an unapproved drug. This follows past non-warning letters and/or inspection reports made public to Liveyon, R3 Stem Cell, Stemell, and others. RAPS has more on the story of the new letter here. This newest …

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Mulling over latest CRISPR tumult, this one from Nat Biot pub on DNA lesions

CRISPR-dart-board

If it seems to you like dramatic cautionary tales about CRISPR accompanied by all sorts of media are coming at us more frequently, it’s not your imagination. In the latest yesterday, it was reported in a new paper led by Allan Bradley that CRISPR-Cas9 results in sometimes large-scale chromosomal lesions at or even away from the …

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